Pneumatosis Intestinalis after Hematopoietic Stem Cell Transplantation: When Not Doing Anything is Good Enough

Retrospective study of 990 pediatric HSCT recipients finds pneumatosis intestinalis in 5.4%, primarily in allogeneic transplant patients on steroids. Unlike necrotizing enterocolitis, PI in this population rarely requires intervention—81% resolved with observation alone in median 15 days, even when pneumoperitoneum present.