Resuscitative endovascular balloon occlusion of the aorta in a pediatric swine model: Is 60 minutes too long?

Swine model study demonstrates that 60 minutes of zone 1 REBOA in pediatric subjects causes persistent metabolic acidosis and organ injury that worsens during critical care, while 30-minute occlusion resolves with resuscitation. Findings suggest prolonged aortic occlusion may cause irreversible physiologic damage in children, contrasting with adult tolerance thresholds.