Whole Blood is Superior to Component Transfusion for Injured Children: A Propensity Matched Analysis

Propensity-matched study of 56 injured children demonstrates whole blood transfusion achieves faster shock resolution (2 vs 6 hours to base deficit correction) and lower post-resuscitation INR compared to component therapy, while requiring less plasma and platelet volume. Findings support whole blood as superior initial resuscitation strategy in pediatric trauma.