miR-200 family expression during normal and abnormal lung development due to congenital diaphragmatic hernia at the later embryonic stage in the nitrofen rat model

Study examines miR-200 family microRNA expression in nitrofen-induced CDH rat model, finding upregulated miR-200a and altered expression patterns in hypoplastic lungs compared to controls. Results suggest disrupted miR-200 family regulation contributes to pulmonary hypoplasia pathogenesis in CDH, offering potential molecular targets for understanding this life-threatening congenital condition.