COMPROMISED DUODENAL MUCOSAL INTEGRITY IN CHILDREN WITH SHORT BOWEL SYNDROME AFTER ADAPTATION TO ENTERAL AUTONOMY

Study of 33 children with short bowel syndrome who achieved enteral autonomy reveals persistent duodenal inflammation and compromised barrier function despite successful weaning from parenteral nutrition. Absence of ileocecal valve and pathologic bowel dilatation further impair mucosal homeostasis, with no evidence of adaptive hyperplasia.