The evolution of early liver biopsy findings in babies with jaundice may delay the diagnosis and treatment of biliary atresia
Author / Expert
Caroline Lemoine, Hector Melin-Aldana, Katherine Brandt, Saeed Mohammad, Riccardo Superina
Topic overview
Abstract
Background
The early diagnosis of biliary atresia (BA) is associated with a better outcome after portoenterostomy. However, very early liver biopsy findings may appear atypical for BA and delay diagnosis. Repeat biopsy histology may change rapidly to show more typical features.
Methods
Between 1997 and 2018, 6 babies with jaundice had more than one biopsy to establish diagnosis. Clinical and histologic data were collected. chi-Square was used for analysis (p
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