Splenic function is not maintained long-term after partial splenectomy in children with sickle cell disease

Retrospective study of 9 pediatric SCD patients demonstrates that partial splenectomy fails to preserve long-term splenic function, with all remnants losing viability by 42 months post-op due to continued autoinfarction. In contrast, all 26 hereditary spherocytosis patients maintained robust remnant perfusion, leading authors to conclude PS is not indicated for splenic preservation in SCD.