Congenital diaphragmatic hernia and associated omphalocele: a study from the CDHSG registry

Analysis of 5,730 CDH cases reveals that the rare combination of congenital diaphragmatic hernia with omphalocele (0.63% incidence) is associated with significantly worse outcomes, including lower survival rates, delayed surgical repair, and increased morbidity. These infants present with greater illness severity at birth but paradoxically receive ECMO less frequently, highlighting complex management challenges from combined pulmonary hypoplasia.