Increased Lymph Node Ratio Predicts Poor Survival in Pediatric Rhabdomyosarcoma
Author / Expert
Ann-Christina Brady, Krishnamurti A. Rao, Rebecca Lane, Lillian Garvin, Juan E. Sola, Eduardo A. Perez
Topic overview
Abstract
Background/Purpose
Lymph Node Ratio (LNR) is defined as the number of positive lymph nodes (pLN) divided by total lymph nodes (LN) examined. LNR correlates with recurrence and/or overall survival in many adult cancers but has not previously been described in pediatric oncologic disease. We hypothesized that LNR correlates with worse disease specific survival (DSS) in pediatric rhabdomyosarcoma (RMS).
Methods
Patients 0.75 (HR 4.32, P = 0.015), alveolar histology (HR 4.797, P
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