Increased Lymph Node Ratio Predicts Poor Survival in Pediatric Rhabdomyosarcoma

Retrospective analysis of 1,076 pediatric rhabdomyosarcoma patients demonstrates that lymph node ratio (LNR) >0.75 independently predicts worse disease-specific survival, with hazard ratio of 4.32. This novel prognostic marker, alongside alveolar histology and advanced stage, may help stratify risk and guide treatment intensity in pediatric RMS.