Human Breast Milk-Derived Extracellular Vesicles in the Protection Against Experimental Necrotizing Enterocolitis

Study demonstrates that extracellular vesicles isolated from human breast milk significantly reduce necrotizing enterocolitis incidence in premature rat models, with enteral administration showing superior protection (88% reduction) compared to intraperitoneal delivery. Findings suggest a novel therapeutic approach for NEC prevention in NICU populations.