Protective effects of lactoferrin on injured intestinal epithelial cells

This in vitro study demonstrates that lactoferrin protects rat and human intestinal epithelial cells from hydrogen peroxide-induced injury by modulating inflammatory markers (IL-6), intestinal stem cell markers (Lgr5), and proliferation pathways (Wnt/β-catenin), providing mechanistic insight into lactoferrin's protective role in necrotizing enterocolitis.