Effect of Wilms tumor histology on response to neoadjuvant chemotherapy
Author / Expert
Seppo Taskinen, Outi Leskinen, Jouko Lohi, Minna Koskenvuo, Mervi Taskinen
Topic overview
Abstract
Purpose
To evaluate the association between Wilms tumor histology at diagnosis and the change in Wilms' tumor volume during preoperative chemotherapy.
Methods
We included all the 52 patients operated for Wilms tumor at 1988–2015, who had both pathology samples and either CT or MRI-images before and after preoperative chemotherapy, available for reevaluation.
Results
The median tumor volume was 586 ml (IQR 323–903) at diagnosis. The median change in tumor volume was −68% (IQR −85 to −40, p
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