Noninvasive assessment of liver fibrosis in pediatric intestinal failure patients using liver stiffness measurement by Vibration-Controlled Transient Elastography

Study of 63 pediatric intestinal failure patients demonstrates that Vibration-Controlled Transient Elastography (VCTE) effectively distinguishes mild from moderate-to-severe liver fibrosis, with liver stiffness measurement ≥6 kPa showing 80% sensitivity and 100% specificity. This noninvasive technique could enable serial monitoring of liver injury in children requiring long-term parenteral nutrition.