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Neurodevelopmental Outcomes and Long-term Quality of Life in Esophageal Atresia: A Narrative Review

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Topic overview

This narrative review examines neurodevelopmental outcomes and quality of life in patients with esophageal atresia, a rare congenital condition often accompanied by tracheoesophageal fistula. With improved survival rates from surgical and critical care advances, the focus has shifted to understanding long-term developmental trajectories and psychosocial well-being in this patient population.

Key takeaways

  • Survival after EA/TEF repair has improved significantly, shifting focus to long-term neurodevelopmental and quality-of-life outcomes.
  • EA patients may experience developmental delays and psychosocial challenges requiring longitudinal multidisciplinary follow-up.
  • Quality of life assessment is now a critical endpoint in EA care, beyond traditional surgical success metrics.
  • Associated congenital anomalies in EA patients contribute to neurodevelopmental risk and require comprehensive screening.
  • Long-term surveillance protocols should address cognitive, behavioral, and psychosocial domains in EA survivors.

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How to cite: GlobalCastMD. Neurodevelopmental Outcomes and Long-term Quality of Life in Esophageal Atresia: A Narrative Review. GlobalCastMD Medical Library. 2026-04-19. https://library.globalcastmd.com/article/11859

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