Cystic fibrosis and portal hypertension: Distal splenorenal shunt can prevent the need for future liver transplant
Author / Expert
Caroline Lemoine, Joan Lokar, Susanna A. McColley, Estella M. Alonso, Riccardo Superina
Topic overview
Abstract
Background
The management of portal hypertension (PHT) in children with well compensated cirrhosis and cystic fibrosis (CF) is controversial. We present our experience with distal splenorenal shunting (DSRS) for the treatment of PHT as an alternative to liver transplantation (LT).
Methods
Between 2008 and 2017, 5 CF children underwent a DSRS at a pediatric hepatobiliary and transplantation referral center. LT (n = 9) was reserved for patients with decompensated cirrhosis. Statistical analysis was done using the paired t-test (p
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