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Letter to Editor Comments on: Antegrade continence enema treatment can lead to proximal colonic dilation while preserving motility in children with constipation

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Topic overview

This letter responds to a study examining colonic motility and dilation in children receiving antegrade continence enema (ACE) therapy for constipation. The authors raise three methodological concerns about the retrospective analysis that found proximal colonic dilation in 20% of patients with longer ACE treatment duration.

Key takeaways

  • ACE treatment may cause proximal colonic dilation in 20% of pediatric patients, particularly with longer treatment duration.
  • Proximal colonic dysmotility was observed in 6% of children undergoing ACE therapy based on contrast enema findings.
  • Methodological concerns exist regarding retrospective ACE studies; clinicians should monitor for proximal complications during treatment.
  • Paired contrast enema data is valuable for assessing anatomical and motility changes in children receiving long-term ACE therapy.

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How to cite: GlobalCastMD. Letter to Editor Comments on: Antegrade continence enema treatment can lead to proximal colonic dilation while preserving motility in children with constipation. GlobalCastMD Medical Library. 2026-03-17. https://library.globalcastmd.com/article/11680

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