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Bedside Surgery in Critically Ill Neonates: Moving Beyond the Mortality Paradox

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Topic overview

This article examines a meta-analysis comparing bedside versus operating room surgery in critically ill neonates, which found higher mortality in bedside cases. The piece critically evaluates the mortality paradox, likely driven by selection bias where the sickest infants undergo bedside procedures due to instability for transport.

Key takeaways

  • - Bedside surgery in critically ill neonates shows 6.8× higher mortality vs OR, but likely reflects selection bias not causation - Sicker neonates unable to tolerate transport are triaged to bedside surgery, confounding mortality comparisons - Current evidence insufficient to conclude bedside surgery is inferior; prospective studies with severity adjustment needed - Transport risk vs surgical environment trade-off requires individualized assessment in unstable neonates - Mortality paradox: bedside surgery may be appropriate for highest-risk patients despite worse aggregate outcomes

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How to cite: GlobalCastMD. Bedside Surgery in Critically Ill Neonates: Moving Beyond the Mortality Paradox. GlobalCastMD Medical Library. 2026-01-27. https://library.globalcastmd.com/article/11424

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