Adherence to a restrictive platelet transfusion guideline in a neonatal surgical population
Author / Expert
Ashley Stoeckel, Erin Soule-Albridge, Henry A. Feldman, Arin Madenci, Martha Sola-Visner, Patricia Davenport
Topic overview
In 2019, the PlaNeT-2 trial reported an increased risk of death and/or major bleeding among neonates transfused with platelets at liberal compared to restrictive thresholds. However, especially in the perioperative setting, clinicians often administer platelet transfusions to neonates at higher platelet count thresholds in hopes of reducing the risk of bleeding. In this study, we investigated if platelet transfusion practices changed in neonates with primary surgical diagnoses after the implementation of a restrictive platelet transfusion guideline in January of 2019.
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