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Acquired Diaphragmatic Hernia Following Pediatric Liver Transplantation: Incidence, Risk Factors, and Surgical Outcomes

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Topic overview

This retrospective study of 246 pediatric liver transplant recipients identified acquired diaphragmatic hernia in 3.3% of cases, with younger age and lower body weight as significant risk factors. Both thoracoscopic and open repair approaches demonstrated favorable short-term outcomes, though standardized screening protocols and predictive models remain needed to identify high-risk patients.

Key takeaways

  • Acquired diaphragmatic hernia occurs in 3.3% of pediatric liver transplant recipients, predominantly in infants under 1 year and those weighing <8 kg
  • Risk factors include younger age at transplant, low body weight, prior abdominal surgery, and left lateral segment grafts
  • Most hernias are right-sided with variable presentation from respiratory symptoms to incidental findings on imaging
  • Thoracoscopic repair is feasible in selected patients with favorable short-term outcomes comparable to open laparotomy
  • Standardized screening protocols and predictive models are needed to identify high-risk patients for early detection

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How to cite: GlobalCastMD. Acquired Diaphragmatic Hernia Following Pediatric Liver Transplantation: Incidence, Risk Factors, and Surgical Outcomes. GlobalCastMD Medical Library. 2026-01-06. https://library.globalcastmd.com/article/11363

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