Improved mortality in gastroschisis patients after implementation of a standardized management bundle in central Malawi: A single-center follow-up at four years
Topic overview
This study demonstrates improved survival outcomes for gastroschisis patients in Malawi following implementation of a standardized management protocol at a tertiary center. The research addresses the significant mortality gap between high-income countries (>90% survival) and sub-Saharan Africa (<20% survival), evaluating predictors of mortality over a four-year period.
Key takeaways
- Standardized care bundles can dramatically improve gastroschisis survival in resource-limited settings in sub-Saharan Africa.
- Gastroschisis mortality remains >80% in much of sub-Saharan Africa despite >90% survival in high-income countries.
- Implementation of protocolized neonatal care at a Malawi tertiary center reduced gastroschisis mortality over four years.
- Identifying modifiable predictors of mortality is critical to closing the survival gap for congenital anomalies in low-resource settings.
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How to cite: GlobalCastMD. Improved mortality in gastroschisis patients after implementation of a standardized management bundle in central Malawi: A single-center follow-up at four years. GlobalCastMD Medical Library. 2025-08-12. https://library.globalcastmd.com/article/11262
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