Transitioning Paediatric Empyema Management: Comparative Efficacy Analysis of tPA and DNase versus Surgical Interventions
Author / Expert
Henri Haapanen, Antti Huuskonen, Tea Nieminen, Tommi Pätilä, Jukka Salminen, Juha Puntila, Svetlana Vakkilainen, Tuula Pelkonen
Topic overview
Empyema significantly impacts paediatric morbidity and imposes a financial burden on healthcare systems. This study evaluates the efficacy of tissue plasminogen activator (tPA) and dornase alpha (DNase) combination in fibrinolytic therapy compared with surgical interventions (VATS/thoracotomy) in children with empyema.
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