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DIAGNOSTIC ACCURACY OF SERUM AND URINARY BIOMARKERS FOR RENAL SCARING IN CHILDREN WITH VESICOURETERAL REFLUX: A SYSTEMATIC REVIEW AND META-ANALYSIS

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Topic overview

This systematic review evaluates non-invasive serum and urinary biomarkers as alternatives to DMSA scintigraphy for detecting renal scarring in pediatric VUR patients. The analysis addresses the need for radiation-free, cost-effective diagnostic tools in managing this common pediatric urological condition.

Key takeaways

  • DMSA scintigraphy remains the gold standard for renal scarring detection but involves radiation exposure and high cost.
  • Serum and urinary biomarkers offer non-invasive alternatives for diagnosing renal scarring in pediatric VUR patients.
  • Meta-analysis evaluates diagnostic accuracy of biomarkers to potentially reduce reliance on imaging in VUR follow-up.

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How to cite: GlobalCastMD. DIAGNOSTIC ACCURACY OF SERUM AND URINARY BIOMARKERS FOR RENAL SCARING IN CHILDREN WITH VESICOURETERAL REFLUX: A SYSTEMATIC REVIEW AND META-ANALYSIS. GlobalCastMD Medical Library. 2025-10-25. https://library.globalcastmd.com/article/11154

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