Internal anal sphincter achalasia in chronic functional constipation in children: A myth rather than reality

Space: StayCurrentMD Author: Alireza S. Keshtgar, Zahra Almatar, Sadaf Kader, Mudher Al-Adnani, Moein Mobini, Haasher Monib, Simran Sehdev Published:

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Alireza S. Keshtgar, Zahra Almatar, Sadaf Kader, Mudher Al-Adnani, Moein Mobini, Haasher Monib, Simran Sehdev

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Internal anal sphincter achalasia (IASA) is characterised by chronic constipation and it is diagnosed based on an absent rectoanal inhibitory reflex (RAIR) on manometry despite a ganglionated rectal biopsy. This study evaluates the pathophysiology of IASA in children with chronic functional constipation (CFC) and determines whether it represents a distinct disorder or a functional variant of constipation.

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