TRACHEAL WORK OF BREATHING IN NEONATES WITH TRACHEOESOPHAGEAL FISTULA BEFORE AND AFTER SURGICAL REPAIR VIA COMPUTATIONAL FLUID DYNAMICS ASSESSMENT

Space: StayCurrentMD Author: Christopher R. Boles, Chamindu C. Gunatilaka, Qiwei Xiao, Jason C. Woods, Paul S. Kingma, Nara S. Higano, Eric A. Nauman, Alister J. Bates Published:

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Christopher R. Boles, Chamindu C. Gunatilaka, Qiwei Xiao, Jason C. Woods, Paul S. Kingma, Nara S. Higano, Eric A. Nauman, Alister J. Bates

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Tracheoesophageal fistula (TEF), often occurring with esophageal atresia (EA), presents significant respiratory challenges in neonates. Neither the effect of EA/TEF, nor the effect of post-surgical complications such as tracheomalacia, on respiratory effort has been previously quantified. This study calculates the tracheal resistive component of work of breathing (TR-WOB) to quantify breathing effort pre- and post-surgical repair of EA/TEF. The primary objective of this study was to calculate the TR-WOB before and after surgical repair and compare it to normal values.

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