Is It Time to Introduce Ex-Situ Normothermic Machine Perfusion in Paediatric Liver Transplantation?

The clinical use of normothermic machine perfusion in liver transplantation currently excludes paediatric recipients due to the challenges of perfusing smaller grafts and risk of portal hyperperfusion injury. This study aimed to evaluate the haemodynamic conditions and histological changes of left lateral segment grafts (LLSG) during long-term normothermic machine perfusion (LT-NMP).