How to deal with rare pediatric surgical diseases in the small developing country with limited resources: Insights from Bosnia and Herzegovina

The European Union Regulation on Orphan Medicinal Products defines a disease/condition as rare if it affects < 1 in 2.000 in the European population [1], making the prevalence data a key tool in creating health care policies for patients with rare diseases (RD) [2]. There is approximately 7.000 RD, mainly genetic [3], affecting approximately 30 million people in Europe and between 25 and 30 million in the United States [4].