Incidence of necrotising enterocolitis before and after introducing routine prophylactic Lactobacillus and Bifidobacterium probiotics
Author / Expert
Arch Dis Child Fetal Neonatal Ed (Robertson C, Savva GM, Clapuci R, Jones J, Maimouni H, Brown E, Minocha A, Hall LJ, Clarke P. - curated by SCHCP)
Topic overview
Objective: To compare rates of necrotising enterocolitis (NEC), late-onset sepsis, and mortality in 5-year epochs before and after implementation of routine daily multistrain probiotics administration in high-risk neonates.
Design: Single-centre retrospective observational study over the 10-year period from 1 January 2008 to 31 December 2017.
Setting: Level 3 neonatal intensive care unit (NICU) of the Norfolk and Norwich University Hospital, UK.
Patients: Preterm neonates at high risk of NEC: admitted to NICU within 3 days of birth at
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