Bedside Surgery in Neonates: Reaffirming the Importance of Contextual Interpretation

We thank Pio et al. [1] for their thoughtful and constructive perspective on our recent meta-analysis comparing bedside and conventional surgery in critically ill neonates [2]. We welcome their clinical interpretation and their highlighting of key considerations that closely align with the cautions we raised in our original report. We agree that mortality differences must always be interpreted within the appropriate clinical context.