Unraveling the Genetic Basis of Omphalocele: A Systematic Review

Omphalocele is one of the most common congenital defects of the abdominal wall. Although a genetic contribution is strongly suspected, the underlying mechanisms remain poorly understood. The aim of this study was to systematically review and analyze genes potentially involved in omphalocele formation, with the objective of clarifying its pathophysiology and identifying key embryological stages.