Letter to the Editor Regarding: Pediatric Complicated Appendicitis: Results of a Standardized Antibiotic Protocol in a Tertiary Center

We have read with great interest the paper, “Pediatric Complicated Appendicitis: Results of a Standardized Antibiotic Protocol in a Tertiary Center”by Estelle Studer et al.[1]. By comparing the first-line regimen of Ceftriaxone/Metronidazole (CM) with the alternative regimen of switching to Piperacillin/Tazobactam (PT) after CM treatment failure, they found that patients with preoperative CRP >150 mg/L and intraoperative intra-abdominal abscess might benefit from shorter hospital stays if PT was chosen as the first-line therapy.