Can Antibiotic Therapy Replace Surgery in Pediatric Acute Uncomplicated Appendicitis? An Updated Meta-Analysis of Randomized Controlled Trials

The efficacy of nonoperative management (NOM) for pediatric uncomplicated appendicitis (UA) remains controversial, with a paucity of large-sample randomized controlled trials (RCTs). This study aims to evaluate the efficacy of NOM for pediatric UA through a meta-analysis of updated RCTs.