Safety and utility of long-acting steroid injection for management of post-operative stricture...
With Dr. Megan Reed Evaurri
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What the experts said
The study was published in 2026 in the Journal of Pediatric Surgery
The study examined institutional experience from 2018 to 2024
50 patients developed post-operative anastomotic stricture: 30 with anorectal malformations and 20 with Hirschsprung disease
70% of patients with anorectal malformations achieved stricture resolution with TAC injections
85% of patients with Hirschsprung disease achieved stricture resolution with TAC injections
The median number of TAC injections needed to achieve stricture resolution was 1 in both groups
30% of anorectal malformation patients required surgery despite TAC injections
10% of Hirschsprung disease patients required surgery despite TAC injections
There were no intraoperative complications from TAC injections
The 30-day complication rate was 2.2%
TAC injections may be a safe, minimally invasive adjunct to traditional dilations with promising rates of stricture resolution and low short-term morbidity
This is a retrospective single center study
TAC injections may be a useful treatment option before moving on to another operation