Association of Prehospital Transfusion With Mortality in Pediatric Trauma

Topic overview

Retrospective cohort study of 559 injured children in Pennsylvania found prehospital blood transfusion associated with significantly reduced 24-hour and in-hospital mortality compared to emergency department transfusion. Propensity-matched analysis showed 46% reduction in 24-hour mortality, supporting early hemostatic resuscitation in pediatric trauma.

Key takeaways

Prehospital blood transfusion reduced 24-hour mortality by 54% (aOR 0.46) compared to ED transfusion in injured children
Number needed to transfuse prehospital is 5 to save one pediatric life in bleeding trauma patients
Early hemostatic resuscitation in the immediate post-injury period shows significant survival benefit in pediatric trauma
Propensity-matched analysis of 207 children demonstrated lower in-hospital mortality (21% vs 32%) with prehospital transfusion

Keywords

Pediatric Trauma Prehospital Transfusion Hemorrhagic Shock Hemostatic Resuscitation Trauma Mortality Emergency Medicine

Hashtags

#PediatricTrauma #PrehospitalCare #TraumaSurgery #HemorrhageControl

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