Taking a STEP back: Assessing the outcomes of multiple STEP procedures
Topic overview
Retrospective study of 17 pediatric short bowel syndrome patients demonstrates that repeat STEP procedures yield diminished outcomes compared to initial STEP, with no patients achieving enteral autonomy after ReSTEP. First STEP resulted in 26% enteral nutrition increase vs 4.7% for ReSTEP, suggesting surgeons should carefully weigh cost-benefit of repeat procedures.
Key takeaways
- Initial STEP procedures achieved 18% PN weaning rate vs 0% for repeat STEPs, with no ReSTEP patients reaching enteral autonomy
- First STEP increased bowel length by 51% vs only 20% for ReSTEP (p=0.02), with diminishing returns on subsequent procedures
- Enteral nutrition tolerance improved 26% after first STEP but only 4.7% after ReSTEP (p=0.03)
- Patient demographics and SBS etiology did not predict need for repeat STEP procedures
- Given higher costs and limited efficacy, surgeons should carefully weigh risks/benefits before performing repeat STEP procedures
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