Wilms Tumor and Other Childhood Kidney Tumors PDQ®

In brief

NCI's evidence-based clinical reference for healthcare professionals managing Wilms tumor (nephroblastoma) and other pediatric renal malignancies. Covers diagnostic evaluation, risk stratification, multimodal treatment approaches including surgery and chemotherapy, and prognostic factors for childhood kidney tumors.

• Wilms tumor is the most common childhood kidney malignancy, requiring multimodal treatment including surgery and chemotherapy.
• Staging and histology guide treatment intensity; favorable histology has excellent prognosis with appropriate therapy.
• Nephron-sparing surgery may be considered in bilateral disease or predisposition syndromes to preserve renal function.

Written by the GCMD Library team from the guideline.