Guideline document
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Topic overview
Clinical approach to diagnosing and treating pleural effusions and empyema, covering diagnostic workup, imaging interpretation, drainage procedures, and management strategies for infected pleural space.
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Medical Management of Pneumonia with Pleural Effusion
Observation DrainCriteria for Observation Only: •Effusion too small to drain (<10 mm)•Effusion drainable, but pt. on antibiotics, no respiratory distress, effusion resolving on serial CXR
Plan: •Baseline CRP , repeat in 24 hours•Repeat CXR in 24 hours if clinically indicated
Criteria to Drain: •Patient with suspected “large” effusion and respiratory compromise•To obtain fluid to further characterize effusion
Diagnostic TapChest Tube PlacementPatient Scenario:•Patient not on antibiotics and mild respiratory distress (identify pathogen)•Clinical presentation atypical for parapneumonic effusion (r/o malignancy, clarify exudate vs. transudate)
Plan: •Tap performed by Pulmor IR•Pleural fluid measurements: pH, glucose, LDH, cell count/differential, gram stain & culture
Patient Scenario:•Patient in respiratory distress•Effusion staged as complicated by U/S or pleural fluid indices (and progressing)
Plan: •IR Consult•Surgery Consult•Pleural fluid measurements: pH, glucose, LDH, cell count/differential, gram stain & culture
See next Page
Updated 1/2019
Surgical ConsultReview U/S with Interventional Radiology/Radiology/Pulmonaryto assess degree of loculations
No significant loculations
Chest tube placed by Interventional Radiology
YesRemove tube in 24-48 hoursNo
Significant loculations
Chest tube placed by Interventional RadiologyStart TPA within 6 hours (Administered Q12H for 6 doses)
No
Continue TPA Consider VATS/Thoracotomy
Yes
•Stop TPA•Remove chest tube in 24 hours
VATS/Thoracotomy at Surgeon discretion (please document reason)
Effusion drained over 75% in 24 hours •Resolution of >75% of effusion•Absence of O2 requirement•Resolution of fever(≥1 of the above)72 hours since 1stTPA dose?Yes
Updated 1/2019
No
Source:•St. Peter SD, et al. Thoracoscopic decortication vs tube thoracostomy with fibrinolysis for empyema in children: a prospective, randomized trial. J PediatrSurg2009;44:106-111.•Gates RL, et al. Drainage, Fibrinolytics or Surgery: A Comparison of Treatment Options in Pediatric Empyema. J PediatrSurg2004;39:1638-1642.
How to cite: GlobalCastMD. Evaluation and Management of Pleural Effusion and Empyema. GlobalCastMD Medical Library. https://library.globalcastmd.com/guideline/4245
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