Steven Scoville

58 timestamped statements across 2 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Soft Tissue Sarcoma (lymph nodes) · guest expert

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▶ Ep 3 · 0:33
Compared to adults, we know that childhood melanoma is associated with delayed diagnosis and therefore, not surprisingly, more frequently has nodal involvement.
quote · Metastatic Disease
▶ Ep 11 · 0:33
Compared to adults, we know that childhood melanoma is associated with delayed diagnosis and therefore, not surprisingly, more frequently has nodal involvement.
quote · Soft Tissue Sarcoma (lymph nodes)
▶ Ep 3 · 4:30
Management of nodal disease had no significant impact on disease outcomes with respect to recurrence or death from disease.
quote · Metastatic Disease
▶ Ep 11 · 4:30
Management of nodal disease had no significant impact on disease outcomes with respect to recurrence or death from disease.
quote · Soft Tissue Sarcoma (lymph nodes)

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Metastatic Disease 29 entries

BOB Ped Surg 2023 - Steven Scoville, IPSO - Presentation

▶ Ep 3 · 0:26
quote Pediatric melanoma has approximately 500 new cases diagnosed annually in children less than or equal to 18 years old. ↗
▶ Ep 3 · 0:26
epidemiological Pediatric melanoma has approximately 500 new cases diagnosed annually in children less than or equal to 18 years old. ↗
▶ Ep 3 · 0:33
clinical Compared to adults, childhood melanoma is associated with delayed diagnosis and more frequently has nodal involvement. ↗
▶ Ep 3 · 0:33
quote Compared to adults, we know that childhood melanoma is associated with delayed diagnosis and therefore, not surprisingly, more frequently has nodal involvement. ↗
▶ Ep 3 · 0:42
clinical Childhood melanoma has unique disease mechanisms compared to adult melanoma. ↗
▶ Ep 3 · 0:44
guideline Management of pediatric melanoma is based on adult studies despite differences from adult disease. ↗
▶ Ep 3 · 0:44
quote Despite these differences though, management of pediatric melanoma is based on adult studies. ↗
▶ Ep 3 · 0:49
guideline Melanoma management is largely based on depth of the tumor and presence of metastatic disease. ↗
▶ Ep 3 · 0:55
guideline Tumors less than 0.8 millimeters thick are largely managed with wide local excision. ↗
▶ Ep 3 · 1:07
guideline Tumors greater than or equal to 0.8 millimeters or less than 0.8 millimeters with high risk features without metastatic involvement typically undergo wide local excision with sentinel lymph node biopsies. ↗
▶ Ep 3 · 1:20
guideline If sentinel lymph node biopsy is positive, patients typically undergo ultrasound observation versus completion lymph node dissection, which has a high risk of morbidity. ↗
▶ Ep 3 · 1:29
clinical Two adult trials (DCOG SLT and MSLT2) showed no significant difference in outcomes for low to intermediate risk patients with positive sentinel lymph node biopsies who were followed with ultrasound observation versus completion lymph node dissections. ↗
▶ Ep 3 · 1:47
clinical There is no pediatric data to support ultrasound observation versus completion lymph node dissection for positive sentinel lymph node biopsies. ↗
▶ Ep 3 · 1:47
quote However, there is no pediatric data to support one versus the other. ↗
▶ Ep 3 · 2:10
epidemiological In this study of 252 pediatric melanoma patients, race was predominantly white, consistent with prior literature. ↗
▶ Ep 3 · 2:21
clinical Breslow depth ranged from tumor in situ to 20 millimeters with a median of 2.55 millimeters. ↗
▶ Ep 3 · 2:40
clinical Of 227 patients who underwent wide local excision with sentinel lymph node biopsies, 115 (approximately 51%) had positive sentinel lymph node biopsies. ↗
▶ Ep 3 · 3:22
clinical Patients who underwent completion lymph node dissection were significantly older than those who underwent ultrasound observation. ↗
▶ Ep 3 · 3:22
clinical Patients who underwent completion lymph node dissection were more likely to receive adjuvant therapy compared to ultrasound observation. ↗
▶ Ep 3 · 3:34
clinical There was no significant difference in recurrence or death from disease between ultrasound observation and completion lymph node dissection groups. ↗
▶ Ep 3 · 3:41
clinical Positive sentinel lymph node biopsies had significantly higher rate of disease recurrence at 18% compared to 3% for negative sentinel lymph node biopsy group. ↗
▶ Ep 3 · 3:52
clinical Only 21% of patients who underwent completion lymph node dissection had additional positive nodal disease. ↗
▶ Ep 3 · 4:01
clinical Rate of recurrence was not significantly different between completion lymph node dissection patients with or without additional nodal burden. ↗
▶ Ep 3 · 4:11
clinical Recurrence was associated with positive sentinel lymph node disease, deeper Breslow depth, greater use of adjuvant therapy, and higher rate of death. ↗
▶ Ep 3 · 4:23
clinical Pediatric melanoma presents as advanced disease with nearly 50% positive sentinel lymph node biopsy rate. ↗
▶ Ep 3 · 4:30
quote Management of nodal disease had no significant impact on disease outcomes with respect to recurrence or death from disease. ↗
▶ Ep 3 · 4:30
clinical Management of nodal disease (ultrasound observation vs completion lymph node dissection) had no significant impact on disease outcomes with respect to recurrence or death from disease. ↗
▶ Ep 3 · 4:38
clinical Findings of additional nodal disease in completion lymph node dissection did not significantly correlate with recurrence. ↗
▶ Ep 3 · 4:47
clinical Recurrence most strongly associated with positive sentinel lymph node biopsies and deeper Breslow depth. ↗
Soft Tissue Sarcoma (lymph nodes) 29 entries

BOB Ped Surg 2023 - Steven Scoville, IPSO - Presentation

▶ Ep 11 · 0:26
epidemiological Pediatric melanoma has approximately 500 new cases diagnosed annually in children less than or equal to 18 years old. ↗
▶ Ep 11 · 0:26
quote Pediatric melanoma has approximately 500 new cases diagnosed annually in children less than or equal to 18 years old. ↗
▶ Ep 11 · 0:33
clinical Compared to adults, childhood melanoma is associated with delayed diagnosis and more frequently has nodal involvement. ↗
▶ Ep 11 · 0:33
quote Compared to adults, we know that childhood melanoma is associated with delayed diagnosis and therefore, not surprisingly, more frequently has nodal involvement. ↗
▶ Ep 11 · 0:42
clinical Childhood melanoma has unique disease mechanisms compared to adult melanoma. ↗
▶ Ep 11 · 0:44
guideline Management of pediatric melanoma is based on adult studies despite differences from adult disease. ↗
▶ Ep 11 · 0:44
quote Despite these differences though, management of pediatric melanoma is based on adult studies. ↗
▶ Ep 11 · 0:49
guideline Melanoma management is largely based on depth of the tumor and presence of metastatic disease. ↗
▶ Ep 11 · 0:55
guideline Tumors less than 0.8 millimeters thick are largely managed with wide local excision. ↗
▶ Ep 11 · 1:07
guideline Tumors greater than or equal to 0.8 millimeters or less than 0.8 millimeters with high risk features without metastatic involvement typically undergo wide local excision with sentinel lymph node biopsies. ↗
▶ Ep 11 · 1:20
guideline If sentinel lymph node biopsy is positive, patients typically undergo ultrasound observation versus completion lymph node dissection, which has a high risk of morbidity. ↗
▶ Ep 11 · 1:29
clinical Two adult trials (DCOG SLT and MSLT2) showed no significant difference in outcomes for low to intermediate risk patients with positive sentinel lymph node biopsies who were followed with ultrasound observation versus completion lymph node dissections. ↗
▶ Ep 11 · 1:47
clinical There is no pediatric data to support ultrasound observation versus completion lymph node dissection for positive sentinel lymph node biopsies. ↗
▶ Ep 11 · 1:47
quote However, there is no pediatric data to support one versus the other. ↗
▶ Ep 11 · 2:10
epidemiological In this study of 252 pediatric melanoma patients, race was predominantly white, consistent with prior literature. ↗
▶ Ep 11 · 2:21
clinical Breslow depth ranged from tumor in situ to 20 millimeters with a median of 2.55 millimeters. ↗
▶ Ep 11 · 2:40
clinical Of 227 patients who underwent wide local excision with sentinel lymph node biopsies, 115 (approximately 51%) had positive sentinel lymph node biopsies. ↗
▶ Ep 11 · 3:22
clinical Patients who underwent completion lymph node dissection were significantly older than those who underwent ultrasound observation. ↗
▶ Ep 11 · 3:22
clinical Patients who underwent completion lymph node dissection were more likely to receive adjuvant therapy compared to ultrasound observation. ↗
▶ Ep 11 · 3:34
clinical There was no significant difference in recurrence or death from disease between ultrasound observation and completion lymph node dissection groups. ↗
▶ Ep 11 · 3:41
clinical Positive sentinel lymph node biopsies had significantly higher rate of disease recurrence at 18% compared to 3% for negative sentinel lymph node biopsy group. ↗
▶ Ep 11 · 3:52
clinical Only 21% of patients who underwent completion lymph node dissection had additional positive nodal disease. ↗
▶ Ep 11 · 4:01
clinical Rate of recurrence was not significantly different between completion lymph node dissection patients with or without additional nodal burden. ↗
▶ Ep 11 · 4:11
clinical Recurrence was associated with positive sentinel lymph node disease, deeper Breslow depth, greater use of adjuvant therapy, and higher rate of death. ↗
▶ Ep 11 · 4:23
clinical Pediatric melanoma presents as advanced disease with nearly 50% positive sentinel lymph node biopsy rate. ↗
▶ Ep 11 · 4:30
clinical Management of nodal disease (ultrasound observation vs completion lymph node dissection) had no significant impact on disease outcomes with respect to recurrence or death from disease. ↗
▶ Ep 11 · 4:30
quote Management of nodal disease had no significant impact on disease outcomes with respect to recurrence or death from disease. ↗
▶ Ep 11 · 4:38
clinical Findings of additional nodal disease in completion lymph node dissection did not significantly correlate with recurrence. ↗
▶ Ep 11 · 4:47
clinical Recurrence most strongly associated with positive sentinel lymph node biopsies and deeper Breslow depth. ↗