Sam Kocoshis

39 timestamped statements across 3 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Intestinal Failure · guest expert Intestinal Rehab · guest expert

Featured diaries

Ep 2 · 1:32:11
Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
quote · Gastroschisis
Ep 1 · 1:32:11
Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
Ep 8 · 1:32:11
Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
Ep 2 · 1:24:14
We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.
quote · Gastroschisis
Ep 1 · 1:24:14
We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.
Ep 8 · 1:24:14
We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.

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Gastroschisis 13 entries

Intestinal Failure - Feeding Access and Nutrition

Ep 2 · 17:15
host_summary In a classic French study by Jolie, adults with short bowel syndrome had 60% absorption with ad lib feeding, 85% with continuous drip feeds, and 75% with half calories by mouth plus overnight drip feeds.
Ep 2 · 41:08
epidemiological Since developing a mature multidisciplinary intestinal rehabilitation program, internal transplant candidates have declined by 75%, and intestinal transplants are almost non-existent.
Ep 2 · 1:02:40
clinical Donor breast milk is less advantageous than maternal breast milk because it is usually from mothers 10-14 months postpartum, has lower caloric density and protein, and freezing may inactivate trophic factors.
Ep 2 · 1:11:51
epidemiological About 60% of patients weaned off TPN have deficiencies in one micronutrient or another.
Ep 2 · 1:23:28
quote The older I get, and I'm pretty old, the more I recommend prebiotics and the less I recommend antibiotics.
Ep 2 · 1:23:28
opinion Prebiotics (oligosaccharides) induce a more healthful flora; probiotics are not routinely recommended due to case reports of central line infections, though these likely occurred through direct line contamination rather than translocation.
Ep 2 · 1:24:14
quote We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.
Ep 2 · 1:30:10
clinical Metronidazole is the wrong choice for bacterial overgrowth because it has limited spectrum, knocks off anaerobes, and facilitates aerobic overgrowth; 2/3 of bloodstream infections were seen in patients on prophylactic Flagyl.
Ep 2 · 1:32:11
quote Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
Ep 2 · 1:32:27
opinion If using antibiotics for bacterial overgrowth, selective decontamination with non-absorbable aminoglycosides (tobramycin) and colistin may be preferable to metronidazole.
Ep 2 · 1:46:00
clinical Cholestyramine in effective doses will bind nutrients, fat-soluble vitamins, and fats, with risk of hyperchloremic acidosis and bezoars; homeopathic doses may improve stool appearance but not reduce volume.
Ep 2 · 1:49:38
clinical In infants, only pancreatic proteases are present in adult quantities; amylases appear between 6-12 months and lipase reaches adult levels by end of first year.
Ep 2 · 1:54:00
host_summary GLP-2 analog can reduce fecal output such that TPN can be reduced by about 20% in 60-70% of adult patients, and totally emancipate about 20% from TPN in extension studies.
Intestinal Failure 13 entries

Intestinal Failure - Feeding Access and Nutrition

Ep 1 · 17:15
host_summary In a classic French study by Jolie, adults with short bowel syndrome had 60% absorption with ad lib feeding, 85% with continuous drip feeds, and 75% with half calories by mouth plus overnight drip feeds.
Ep 1 · 41:08
epidemiological Since developing a mature multidisciplinary intestinal rehabilitation program, internal transplant candidates have declined by 75%, and intestinal transplants are almost non-existent.
Ep 1 · 1:02:40
clinical Donor breast milk is less advantageous than maternal breast milk because it is usually from mothers 10-14 months postpartum, has lower caloric density and protein, and freezing may inactivate trophic factors.
Ep 1 · 1:11:51
epidemiological About 60% of patients weaned off TPN have deficiencies in one micronutrient or another.
Ep 1 · 1:23:28
opinion Prebiotics (oligosaccharides) induce a more healthful flora; probiotics are not routinely recommended due to case reports of central line infections, though these likely occurred through direct line contamination rather than translocation.
Ep 1 · 1:23:28
quote The older I get, and I'm pretty old, the more I recommend prebiotics and the less I recommend antibiotics.
Ep 1 · 1:24:14
quote We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.
Ep 1 · 1:30:10
clinical Metronidazole is the wrong choice for bacterial overgrowth because it has limited spectrum, knocks off anaerobes, and facilitates aerobic overgrowth; 2/3 of bloodstream infections were seen in patients on prophylactic Flagyl.
Ep 1 · 1:32:11
quote Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
Ep 1 · 1:32:27
opinion If using antibiotics for bacterial overgrowth, selective decontamination with non-absorbable aminoglycosides (tobramycin) and colistin may be preferable to metronidazole.
Ep 1 · 1:46:00
clinical Cholestyramine in effective doses will bind nutrients, fat-soluble vitamins, and fats, with risk of hyperchloremic acidosis and bezoars; homeopathic doses may improve stool appearance but not reduce volume.
Ep 1 · 1:49:38
clinical In infants, only pancreatic proteases are present in adult quantities; amylases appear between 6-12 months and lipase reaches adult levels by end of first year.
Ep 1 · 1:54:00
host_summary GLP-2 analog can reduce fecal output such that TPN can be reduced by about 20% in 60-70% of adult patients, and totally emancipate about 20% from TPN in extension studies.
Intestinal Rehab 13 entries

Intestinal Failure - Feeding Access and Nutrition

Ep 8 · 17:15
host_summary In a classic French study by Jolie, adults with short bowel syndrome had 60% absorption with ad lib feeding, 85% with continuous drip feeds, and 75% with half calories by mouth plus overnight drip feeds.
Ep 8 · 41:08
epidemiological Since developing a mature multidisciplinary intestinal rehabilitation program, internal transplant candidates have declined by 75%, and intestinal transplants are almost non-existent.
Ep 8 · 1:02:40
clinical Donor breast milk is less advantageous than maternal breast milk because it is usually from mothers 10-14 months postpartum, has lower caloric density and protein, and freezing may inactivate trophic factors.
Ep 8 · 1:11:51
epidemiological About 60% of patients weaned off TPN have deficiencies in one micronutrient or another.
Ep 8 · 1:23:28
opinion Prebiotics (oligosaccharides) induce a more healthful flora; probiotics are not routinely recommended due to case reports of central line infections, though these likely occurred through direct line contamination rather than translocation.
Ep 8 · 1:23:28
quote The older I get, and I'm pretty old, the more I recommend prebiotics and the less I recommend antibiotics.
Ep 8 · 1:24:14
quote We need to discourage putrefactive bacteria such as E. coli, Klebsiella, and the like, and we want to encourage the anaerobes.
Ep 8 · 1:30:10
clinical Metronidazole is the wrong choice for bacterial overgrowth because it has limited spectrum, knocks off anaerobes, and facilitates aerobic overgrowth; 2/3 of bloodstream infections were seen in patients on prophylactic Flagyl.
Ep 8 · 1:32:11
quote Metronidazole is absolutely the wrong choice. It has a limited spectrum. It knocks off your anaerobes and facilitates the growth of aerobes.
Ep 8 · 1:32:27
opinion If using antibiotics for bacterial overgrowth, selective decontamination with non-absorbable aminoglycosides (tobramycin) and colistin may be preferable to metronidazole.
Ep 8 · 1:46:00
clinical Cholestyramine in effective doses will bind nutrients, fat-soluble vitamins, and fats, with risk of hyperchloremic acidosis and bezoars; homeopathic doses may improve stool appearance but not reduce volume.
Ep 8 · 1:49:38
clinical In infants, only pancreatic proteases are present in adult quantities; amylases appear between 6-12 months and lipase reaches adult levels by end of first year.
Ep 8 · 1:54:00
host_summary GLP-2 analog can reduce fecal output such that TPN can be reduced by about 20% in 60-70% of adult patients, and totally emancipate about 20% from TPN in extension studies.