Roshni Dasgupta

63 timestamped statements across 2 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Sarcoma (Ewing/Rhabdo) · guest expert

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▶ Ep 2 · 5:52
You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know.
quote · Osteosarcoma
▶ Ep 18 · 5:52
You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know.
quote · Sarcoma (Ewing/Rhabdo)
▶ Ep 18 · 5:52
You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know.
quote · Sarcoma (Ewing/Rhabdo)
▶ Ep 2 · 3:19
You will find about 30 to 40% more lung nodules with your fingers and looking than you actually find on CAT scan, even with our special MP scanning and our like thin cut CT scans.
quote · Osteosarcoma

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Osteosarcoma 21 entries

Update Course Rewind: Thoracotomy vs VATS for Lung Metastases

▶ Ep 2 · 2:08
quote About 40% of patients, you can get a. Durable cure response after 5 years. If you have complete metastatic site clearance, you can make these patients long-term survivors. ↗
▶ Ep 2 · 2:08
clinical About 40% of patients can achieve a durable cure response after 5 years with complete metastatic site clearance. ↗
▶ Ep 2 · 2:23
clinical Complete surgical resection of all metastatic tumor sites is an independent positive prognostic factor and affects overall survival, not just disease recurrence. ↗
▶ Ep 2 · 2:35
clinical In patients with metastatic osteosarcoma, even 1-millimeter nodules can contain malignant disease in about 60% of cases. ↗
▶ Ep 2 · 2:35
quote Our data actually from one of our PSA studies shows that even at the size of 1 millimeter, you can get about 60% of 1 millimeter nodules contained malignant disease. ↗
▶ Ep 2 · 2:47
clinical The bigger the nodule is, the more likely it contains malignancy, but all the way down to 1 millimeter, tumor can be found. ↗
▶ Ep 2 · 3:13
clinical Thoracotomy has historically been standard of care because surgeons can use fingers and hands to feel tiny nodules. ↗
▶ Ep 2 · 3:19
quote You will find about 30 to 40% more lung nodules with your fingers and looking than you actually find on CAT scan, even with our special MP scanning and our like thin cut CT scans. ↗
▶ Ep 2 · 3:19
clinical Manual palpation during thoracotomy finds about 30 to 40% more lung nodules than are detected on CT scan, even with thin-cut CT scans. ↗
▶ Ep 2 · 3:50
clinical ICG can be used with thoracotomy to find deeper nodules, though depth of penetration is a limitation. ↗
▶ Ep 2 · 4:15
opinion It is uncertain whether removing tiny 1-millimeter nodules actually provides a survival advantage. ↗
▶ Ep 2 · 4:41
clinical VATS is minimally invasive with shorter length of stay, and repeat thoracoscopy typically encounters fewer adhesions compared to repeat thoracotomy. ↗
▶ Ep 2 · 4:58
clinical VATS often requires some sort of localization process and good interventional radiology support. ↗
▶ Ep 2 · 5:34
clinical In oligometastatic disease (patients with fewer than 4 nodules on each side), there was no difference in mortality between open resection and thoracoscopy. ↗
▶ Ep 2 · 5:34
quote Um, which really tells you that an oligometastatic disease, meaning that patients who have less than 4 nodules on each side, there was no difference in terms of mortality. ↗
▶ Ep 2 · 5:44
clinical The survival curves for thoracotomy and thoracoscopy in oligometastatic disease are essentially identical, meaning the optimal operation is unknown. ↗
▶ Ep 2 · 5:52
quote You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know. ↗
▶ Ep 2 · 6:03
epidemiological The multi-institution study had significant selection bias and institutional selection bias, with patients unlikely to receive thoracoscopy if they had many nodules. ↗
▶ Ep 2 · 6:34
clinical Metastatic disease is typically addressed after 4 cycles of chemotherapy, and residual nodules at that point are unlikely to change with additional chemotherapy. ↗
▶ Ep 2 · 7:02
clinical Practice for bilateral lung metastases is highly varied, with options including median sternotomy, staged thoracotomies, or bilateral thoracoscopies. ↗
▶ Ep 2 · 7:13
clinical Most practitioners perform staged procedures for bilateral disease, particularly with thoracotomy, typically 4 to 6 weeks apart to allow a cycle of chemotherapy in between. ↗
Sarcoma (Ewing/Rhabdo) 42 entries

Update Course Rewind: Thoracotomy vs VATS for Lung Metastases

▶ Ep 18 · 2:08
clinical About 40% of patients can achieve a durable cure response after 5 years with complete metastatic site clearance. ↗
▶ Ep 18 · 2:08
quote About 40% of patients, you can get a. Durable cure response after 5 years. If you have complete metastatic site clearance, you can make these patients long-term survivors. ↗
▶ Ep 18 · 2:08
clinical About 40% of patients can achieve a durable cure response after 5 years with complete metastatic site clearance. ↗
▶ Ep 18 · 2:08
quote About 40% of patients, you can get a. Durable cure response after 5 years. If you have complete metastatic site clearance, you can make these patients long-term survivors. ↗
▶ Ep 18 · 2:23
clinical Complete surgical resection of all metastatic tumor sites is an independent positive prognostic factor and affects overall survival, not just disease recurrence. ↗
▶ Ep 18 · 2:23
clinical Complete surgical resection of all metastatic tumor sites is an independent positive prognostic factor and affects overall survival, not just disease recurrence. ↗
▶ Ep 18 · 2:35
clinical In patients with metastatic osteosarcoma, even 1-millimeter nodules can contain malignant disease in about 60% of cases. ↗
▶ Ep 18 · 2:35
quote Our data actually from one of our PSA studies shows that even at the size of 1 millimeter, you can get about 60% of 1 millimeter nodules contained malignant disease. ↗
▶ Ep 18 · 2:35
clinical In patients with metastatic osteosarcoma, even 1-millimeter nodules can contain malignant disease in about 60% of cases. ↗
▶ Ep 18 · 2:35
quote Our data actually from one of our PSA studies shows that even at the size of 1 millimeter, you can get about 60% of 1 millimeter nodules contained malignant disease. ↗
▶ Ep 18 · 2:47
clinical The bigger the nodule is, the more likely it contains malignancy, but all the way down to 1 millimeter, tumor can be found. ↗
▶ Ep 18 · 2:47
clinical The bigger the nodule is, the more likely it contains malignancy, but all the way down to 1 millimeter, tumor can be found. ↗
▶ Ep 18 · 3:13
clinical Thoracotomy has historically been standard of care because surgeons can use fingers and hands to feel tiny nodules. ↗
▶ Ep 18 · 3:13
clinical Thoracotomy has historically been standard of care because surgeons can use fingers and hands to feel tiny nodules. ↗
▶ Ep 18 · 3:19
clinical Manual palpation during thoracotomy finds about 30 to 40% more lung nodules than are detected on CT scan, even with thin-cut CT scans. ↗
▶ Ep 18 · 3:19
quote You will find about 30 to 40% more lung nodules with your fingers and looking than you actually find on CAT scan, even with our special MP scanning and our like thin cut CT scans. ↗
▶ Ep 18 · 3:19
clinical Manual palpation during thoracotomy finds about 30 to 40% more lung nodules than are detected on CT scan, even with thin-cut CT scans. ↗
▶ Ep 18 · 3:19
quote You will find about 30 to 40% more lung nodules with your fingers and looking than you actually find on CAT scan, even with our special MP scanning and our like thin cut CT scans. ↗
▶ Ep 18 · 3:50
clinical ICG can be used with thoracotomy to find deeper nodules, though depth of penetration is a limitation. ↗
▶ Ep 18 · 3:50
clinical ICG can be used with thoracotomy to find deeper nodules, though depth of penetration is a limitation. ↗
▶ Ep 18 · 4:15
opinion It is uncertain whether removing tiny 1-millimeter nodules actually provides a survival advantage. ↗
▶ Ep 18 · 4:15
opinion It is uncertain whether removing tiny 1-millimeter nodules actually provides a survival advantage. ↗
▶ Ep 18 · 4:41
clinical VATS is minimally invasive with shorter length of stay, and repeat thoracoscopy typically encounters fewer adhesions compared to repeat thoracotomy. ↗
▶ Ep 18 · 4:41
clinical VATS is minimally invasive with shorter length of stay, and repeat thoracoscopy typically encounters fewer adhesions compared to repeat thoracotomy. ↗
▶ Ep 18 · 4:58
clinical VATS often requires some sort of localization process and good interventional radiology support. ↗
▶ Ep 18 · 4:58
clinical VATS often requires some sort of localization process and good interventional radiology support. ↗
▶ Ep 18 · 5:34
clinical In oligometastatic disease (patients with fewer than 4 nodules on each side), there was no difference in mortality between open resection and thoracoscopy. ↗
▶ Ep 18 · 5:34
quote Um, which really tells you that an oligometastatic disease, meaning that patients who have less than 4 nodules on each side, there was no difference in terms of mortality. ↗
▶ Ep 18 · 5:34
quote Um, which really tells you that an oligometastatic disease, meaning that patients who have less than 4 nodules on each side, there was no difference in terms of mortality. ↗
▶ Ep 18 · 5:34
clinical In oligometastatic disease (patients with fewer than 4 nodules on each side), there was no difference in mortality between open resection and thoracoscopy. ↗
▶ Ep 18 · 5:44
clinical The survival curves for thoracotomy and thoracoscopy in oligometastatic disease are essentially identical, meaning the optimal operation is unknown. ↗
▶ Ep 18 · 5:44
clinical The survival curves for thoracotomy and thoracoscopy in oligometastatic disease are essentially identical, meaning the optimal operation is unknown. ↗
▶ Ep 18 · 5:52
quote You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know. ↗
▶ Ep 18 · 5:52
quote You know, sort of from a cancer surgeon perspective, you're like, I need to get all the tumor out all the time, but when you actually look at the data, maybe those small little nodules that you're feeling with a grain of sand don't actually make that much difference, and we don't know. ↗
▶ Ep 18 · 6:03
epidemiological The multi-institution study had significant selection bias and institutional selection bias, with patients unlikely to receive thoracoscopy if they had many nodules. ↗
▶ Ep 18 · 6:03
epidemiological The multi-institution study had significant selection bias and institutional selection bias, with patients unlikely to receive thoracoscopy if they had many nodules. ↗
▶ Ep 18 · 6:34
clinical Metastatic disease is typically addressed after 4 cycles of chemotherapy, and residual nodules at that point are unlikely to change with additional chemotherapy. ↗
▶ Ep 18 · 6:34
clinical Metastatic disease is typically addressed after 4 cycles of chemotherapy, and residual nodules at that point are unlikely to change with additional chemotherapy. ↗
▶ Ep 18 · 7:02
clinical Practice for bilateral lung metastases is highly varied, with options including median sternotomy, staged thoracotomies, or bilateral thoracoscopies. ↗
▶ Ep 18 · 7:02
clinical Practice for bilateral lung metastases is highly varied, with options including median sternotomy, staged thoracotomies, or bilateral thoracoscopies. ↗
▶ Ep 18 · 7:13
clinical Most practitioners perform staged procedures for bilateral disease, particularly with thoracotomy, typically 4 to 6 weeks apart to allow a cycle of chemotherapy in between. ↗
▶ Ep 18 · 7:13
clinical Most practitioners perform staged procedures for bilateral disease, particularly with thoracotomy, typically 4 to 6 weeks apart to allow a cycle of chemotherapy in between. ↗