66 timestamped statements
across 2 collections
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▶Ep 20 · 13:30
Increasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.
Increasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.
Increasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.
Increasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they age.
Outcomes and Complications in Hirschsprung Disease
▶Ep 20 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number allowing tracking of patients and access to their complete medical history from national records.↗
▶Ep 20 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number allowing tracking of patients and access to their complete medical history from national records.↗
▶Ep 20 · 3:55
quoteWe have a social security number for all Finns. And we can track all our patients back. We know their whereabouts and we also know their sort of medical history from the national records.↗
▶Ep 20 · 3:55
quoteWe have a social security number for all Finns. And we can track all our patients back. We know their whereabouts and we also know their sort of medical history from the national records.↗
▶Ep 20 · 9:36
epidemiologicalIn a population-based study of 143 adult Hirschsprung patients (operated 1960-1986), the mean bowel function score was 17.1 compared to 19.1 in controls (p<0.05), with only 25% of patients scoring full 20 points versus 50% of controls.↗
▶Ep 20 · 9:36
epidemiologicalIn a population-based study of 143 adult Hirschsprung patients (operated 1960-1986), the mean bowel function score was 17.1 compared to 19.1 in controls (p<0.05), with only 25% of patients scoring full 20 points versus 50% of controls.↗
▶Ep 20 · 10:07
epidemiological30% of adult Hirschsprung patients report frequent soiling, 2% had accidents, and 10% had complications requiring treatment.↗
▶Ep 20 · 10:07
epidemiological30% of adult Hirschsprung patients report frequent soiling, 2% had accidents, and 10% had complications requiring treatment.↗
▶Ep 20 · 11:40
epidemiologicalOverall gastrointestinal quality of life in adult Hirschsprung patients appears comparable to controls, though 22% had scores lower than 110 indicating poor GI quality of life.↗
▶Ep 20 · 11:40
epidemiologicalOverall gastrointestinal quality of life in adult Hirschsprung patients appears comparable to controls, though 22% had scores lower than 110 indicating poor GI quality of life.↗
▶Ep 20 · 13:30
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel score in patients but not controls.↗
▶Ep 20 · 13:30
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.↗
▶Ep 20 · 13:30
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel score in patients but not controls.↗
▶Ep 20 · 13:30
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.↗
▶Ep 20 · 23:11
quoteIntended beyond 50 centimeters of this island, the achievement of functional in continuity or autonomy is exceptional and long-term survival poor without transportation.↗
▶Ep 20 · 23:11
quoteIntended beyond 50 centimeters of this island, the achievement of functional in continuity or autonomy is exceptional and long-term survival poor without transportation.↗
▶Ep 20 · 23:11
clinicalPatients with aganglionosis extending beyond 50 centimeters of terminal ileum have exceptional difficulty achieving functional bowel continuity or autonomy, and poor long-term survival without transplantation.↗
▶Ep 20 · 23:11
clinicalPatients with aganglionosis extending beyond 50 centimeters of terminal ileum have exceptional difficulty achieving functional bowel continuity or autonomy, and poor long-term survival without transplantation.↗
▶Ep 20 · 23:27
clinicalIf aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox and metronidazole.↗
▶Ep 20 · 23:27
clinicalIf aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox and metronidazole.↗
▶Ep 20 · 24:28
clinicalIn Finland, patients with total colonic aganglionosis are routinely tested for RET mutations.↗
▶Ep 20 · 24:28
clinicalIn Finland, patients with total colonic aganglionosis are routinely tested for RET mutations.↗
Hirschsprung Disease: Cases and Complications
▶Ep 41 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number that allows tracking of patients and access to their complete medical history from national records throughout their lifetime.↗
▶Ep 41 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number that allows tracking of patients and access to their complete medical history from national records throughout their lifetime.↗
▶Ep 41 · 9:36
epidemiologicalIn the Finnish adult Hirschsprung study (patients operated 1960-1986), the mean bowel function score was 17.1 in patients versus 19.1 in controls (p<0.05), with lower scores indicating worse function.↗
▶Ep 41 · 9:36
epidemiologicalIn the Finnish adult Hirschsprung study (patients operated 1960-1986), the mean bowel function score was 17.1 in patients versus 19.1 in controls (p<0.05), with lower scores indicating worse function.↗
▶Ep 41 · 9:53
epidemiologicalIn the Finnish study, 25% of adult Hirschsprung patients scored the full 20 points on bowel function versus 50% of controls; 13% reported frequent soiling, 2% had fecal accidents, and 10% had complications requiring treatment.↗
▶Ep 41 · 9:53
epidemiologicalIn the Finnish study, 25% of adult Hirschsprung patients scored the full 20 points on bowel function versus 50% of controls; 13% reported frequent soiling, 2% had fecal accidents, and 10% had complications requiring treatment.↗
▶Ep 41 · 11:31
epidemiologicalOverall gastrointestinal quality of life (GIQLI score) in adult Hirschsprung patients was mostly at the same level as healthy controls, though 22% of patients had scores below 110 indicating poor quality of life.↗
▶Ep 41 · 11:31
epidemiologicalOverall gastrointestinal quality of life (GIQLI score) in adult Hirschsprung patients was mostly at the same level as healthy controls, though 22% of patients had scores below 110 indicating poor quality of life.↗
▶Ep 41 · 13:29
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel function score in patients but not controls—a worrying finding suggesting patients may deteriorate as they age.↗
▶Ep 41 · 13:29
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel function score in patients but not controls—a worrying finding suggesting patients may deteriorate as they age.↗
▶Ep 41 · 13:51
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they age.↗
▶Ep 41 · 13:51
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they age.↗
▶Ep 41 · 23:11
quoteIntended and nois beyond 50 centimeters of of of this island, the achievement of functional continuity or autonomy is exceptional and long-term survival poor without interstellar transportation.↗
▶Ep 41 · 23:11
clinicalIn patients with total colonic aganglionosis, if aganglionosis extends beyond 50 cm of terminal ileum, achievement of functional bowel continuity or autonomy from parenteral nutrition is exceptional and long-term survival is poor without intestinal transplantation.↗
▶Ep 41 · 23:11
quoteIntended and nois beyond 50 centimeters of of of this island, the achievement of functional continuity or autonomy is exceptional and long-term survival poor without interstellar transportation.↗
▶Ep 41 · 23:11
clinicalIn patients with total colonic aganglionosis, if aganglionosis extends beyond 50 cm of terminal ileum, achievement of functional bowel continuity or autonomy from parenteral nutrition is exceptional and long-term survival is poor without intestinal transplantation.↗
▶Ep 41 · 23:27
clinicalWhen aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox injections and metronidazole.↗
▶Ep 41 · 23:27
quoteIf the egg gangnosis is, this is outlook of bowel function is reassuring after a pouch anal anastomosis, although obstructive symptoms and enteritis are frequent but manageable with Botox and metronidazole.↗
▶Ep 41 · 23:27
quoteIf the egg gangnosis is, this is outlook of bowel function is reassuring after a pouch anal anastomosis, although obstructive symptoms and enteritis are frequent but manageable with Botox and metronidazole.↗
▶Ep 41 · 23:27
clinicalWhen aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox injections and metronidazole.↗
▶Ep 41 · 24:35
clinicalIn Finland, RET mutation testing is performed in Hirschsprung patients.↗
▶Ep 41 · 24:35
clinicalIn Finland, RET mutation testing is performed in Hirschsprung patients.↗
Outcomes and Complications in Hirschsprung Disease
▶Ep 4 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number allowing tracking of patients and access to their complete medical history from national records.↗
▶Ep 4 · 3:55
quoteWe have a social security number for all Finns. And we can track all our patients back. We know their whereabouts and we also know their sort of medical history from the national records.↗
▶Ep 4 · 9:36
epidemiologicalIn a population-based study of 143 adult Hirschsprung patients (operated 1960-1986), the mean bowel function score was 17.1 compared to 19.1 in controls (p<0.05), with only 25% of patients scoring full 20 points versus 50% of controls.↗
▶Ep 4 · 10:07
epidemiological30% of adult Hirschsprung patients report frequent soiling, 2% had accidents, and 10% had complications requiring treatment.↗
▶Ep 4 · 11:40
epidemiologicalOverall gastrointestinal quality of life in adult Hirschsprung patients appears comparable to controls, though 22% had scores lower than 110 indicating poor GI quality of life.↗
▶Ep 4 · 13:30
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel score in patients but not controls.↗
▶Ep 4 · 13:30
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they when they age.↗
▶Ep 4 · 23:11
quoteIntended beyond 50 centimeters of this island, the achievement of functional in continuity or autonomy is exceptional and long-term survival poor without transportation.↗
▶Ep 4 · 23:11
clinicalPatients with aganglionosis extending beyond 50 centimeters of terminal ileum have exceptional difficulty achieving functional bowel continuity or autonomy, and poor long-term survival without transplantation.↗
▶Ep 4 · 23:27
clinicalIf aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox and metronidazole.↗
▶Ep 4 · 24:28
clinicalIn Finland, patients with total colonic aganglionosis are routinely tested for RET mutations.↗
Hirschsprung Disease: Cases and Complications
▶Ep 7 · 3:51
epidemiologicalFinland can conduct long-term follow-up studies because all Finns have a social security number that allows tracking of patients and access to their complete medical history from national records throughout their lifetime.↗
▶Ep 7 · 9:36
epidemiologicalIn the Finnish adult Hirschsprung study (patients operated 1960-1986), the mean bowel function score was 17.1 in patients versus 19.1 in controls (p<0.05), with lower scores indicating worse function.↗
▶Ep 7 · 9:53
epidemiologicalIn the Finnish study, 25% of adult Hirschsprung patients scored the full 20 points on bowel function versus 50% of controls; 13% reported frequent soiling, 2% had fecal accidents, and 10% had complications requiring treatment.↗
▶Ep 7 · 11:31
epidemiologicalOverall gastrointestinal quality of life (GIQLI score) in adult Hirschsprung patients was mostly at the same level as healthy controls, though 22% of patients had scores below 110 indicating poor quality of life.↗
▶Ep 7 · 13:29
epidemiologicalIncreasing age was the only significant predictor of poor functional outcome in adult Hirschsprung patients, and age was inversely related to bowel function score in patients but not controls—a worrying finding suggesting patients may deteriorate as they age.↗
▶Ep 7 · 13:51
quoteIncreasing age was the only significant predictor of poor functional outcome. And we also found that age was inversely related to the bowel score in the patients but not in controls, and this is sort of a worrying finding, which means that we may expect that our patients that might do quite well when they're young adults might not do so well when they age.↗
▶Ep 7 · 23:11
clinicalIn patients with total colonic aganglionosis, if aganglionosis extends beyond 50 cm of terminal ileum, achievement of functional bowel continuity or autonomy from parenteral nutrition is exceptional and long-term survival is poor without intestinal transplantation.↗
▶Ep 7 · 23:11
quoteIntended and nois beyond 50 centimeters of of of this island, the achievement of functional continuity or autonomy is exceptional and long-term survival poor without interstellar transportation.↗
▶Ep 7 · 23:27
quoteIf the egg gangnosis is, this is outlook of bowel function is reassuring after a pouch anal anastomosis, although obstructive symptoms and enteritis are frequent but manageable with Botox and metronidazole.↗
▶Ep 7 · 23:27
clinicalWhen aganglionosis is limited to the colon, the outlook for bowel function after pouch-anal anastomosis is reassuring, although obstructive symptoms and enterocolitis are frequent but manageable with Botox injections and metronidazole.↗
▶Ep 7 · 24:35
clinicalIn Finland, RET mutation testing is performed in Hirschsprung patients.↗