I think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.
I think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.
I think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.
I think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.
I think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.
I think one of the other things when you speak to the family, it's really important to reassure them that even if the mass increases in size and you take it out, it is likely to be a very, very low risk tumor.
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 2 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 2 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 2 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 2 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 2 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 2 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 2 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 2 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 2 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 2 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 2 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 2 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 2 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 2 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 2 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 2 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 2 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 2 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 2 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 2 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 2 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 2 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 2 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 2 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 2 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 2 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
▶Ep 2 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 74 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 74 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 74 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 74 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 74 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 74 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 74 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 74 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 74 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 74 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 74 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 74 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 74 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 74 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 74 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 74 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 74 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 74 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 74 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 74 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 74 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 74 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 74 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 74 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 74 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 74 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
▶Ep 74 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
Colorectal Quiz Episode 37: The Yancey-Soave story of the original surgical descriptions for Hirschsprung disease
▶Ep 136 · 1:35
quoteI never learned about Dr. Yancey when I was training in general surgery and when I was doing my fellowship in pediatric surgery.↗
▶Ep 136 · 1:35
quoteI never learned about Dr. Yancey when I was training in general surgery and when I was doing my fellowship in pediatric surgery.↗
▶Ep 136 · 7:05
epidemiologicalIn 1951-1952, Black academics could not publish their work in mainstream surgical journals.↗
▶Ep 136 · 7:05
quoteI think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.↗
▶Ep 136 · 7:05
quoteI think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.↗
▶Ep 136 · 7:05
epidemiologicalIn 1951-1952, Black academics could not publish their work in mainstream surgical journals.↗
▶Ep 136 · 12:26
clinicalThe Hirschsprung interest group members write papers, review manuscripts for journals, write board questions, and influence CPT coding.↗
▶Ep 136 · 12:26
clinicalThe Hirschsprung interest group members write papers, review manuscripts for journals, write board questions, and influence CPT coding.↗
▶Ep 136 · 12:26
quoteI basically just bombarded the meeting because I don't even think you guys had invited me. I think I just came in and asked for five minutes or 10 minutes on the agenda.↗
▶Ep 136 · 12:26
quoteI basically just bombarded the meeting because I don't even think you guys had invited me. I think I just came in and asked for five minutes or 10 minutes on the agenda.↗
▶Ep 136 · 14:30
clinicalWhen reviewing articles for journals, Dr. Newman now sends back revisions to ensure correct references to Dr. Yancey's work are included.↗
▶Ep 136 · 14:30
clinicalWhen reviewing articles for journals, Dr. Newman now sends back revisions to ensure correct references to Dr. Yancey's work are included.↗
▶Ep 136 · 14:51
quoteWhen I review a article for a journal, I send back revisions, including, you know, making sure to use the correct references.↗
▶Ep 136 · 14:51
quoteWhen I review a article for a journal, I send back revisions, including, you know, making sure to use the correct references.↗
Colorectal Quiz Episode 37: The Yancey-Soave story of the original surgical descriptions for Hirschsprung disease
▶Ep 4 · 1:35
quoteI never learned about Dr. Yancey when I was training in general surgery and when I was doing my fellowship in pediatric surgery.↗
▶Ep 4 · 7:05
epidemiologicalIn 1951-1952, Black academics could not publish their work in mainstream surgical journals.↗
▶Ep 4 · 7:05
quoteI think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.↗
▶Ep 4 · 12:26
clinicalThe Hirschsprung interest group members write papers, review manuscripts for journals, write board questions, and influence CPT coding.↗
▶Ep 4 · 12:26
quoteI basically just bombarded the meeting because I don't even think you guys had invited me. I think I just came in and asked for five minutes or 10 minutes on the agenda.↗
▶Ep 4 · 14:30
clinicalWhen reviewing articles for journals, Dr. Newman now sends back revisions to ensure correct references to Dr. Yancey's work are included.↗
▶Ep 4 · 14:51
quoteWhen I review a article for a journal, I send back revisions, including, you know, making sure to use the correct references.↗
Colorectal Quiz Episode 37: The Yancey-Soave story of the original surgical descriptions for Hirschsprung disease
▶Ep 56 · 1:35
quoteI never learned about Dr. Yancey when I was training in general surgery and when I was doing my fellowship in pediatric surgery.↗
▶Ep 56 · 1:35
quoteI never learned about Dr. Yancey when I was training in general surgery and when I was doing my fellowship in pediatric surgery.↗
▶Ep 56 · 7:05
epidemiologicalIn 1951-1952, Black academics could not publish their work in mainstream surgical journals.↗
▶Ep 56 · 7:05
quoteI think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.↗
▶Ep 56 · 7:05
epidemiologicalIn 1951-1952, Black academics could not publish their work in mainstream surgical journals.↗
▶Ep 56 · 7:05
quoteI think that this is an example of sort of some of the historical structural inequities that we know exist, where in 1951 and 1952, you know, Black academics could not publish their work in mainstream journals.↗
▶Ep 56 · 12:26
clinicalThe Hirschsprung interest group members write papers, review manuscripts for journals, write board questions, and influence CPT coding.↗
▶Ep 56 · 12:26
quoteI basically just bombarded the meeting because I don't even think you guys had invited me. I think I just came in and asked for five minutes or 10 minutes on the agenda.↗
▶Ep 56 · 12:26
quoteI basically just bombarded the meeting because I don't even think you guys had invited me. I think I just came in and asked for five minutes or 10 minutes on the agenda.↗
▶Ep 56 · 12:26
clinicalThe Hirschsprung interest group members write papers, review manuscripts for journals, write board questions, and influence CPT coding.↗
▶Ep 56 · 14:30
clinicalWhen reviewing articles for journals, Dr. Newman now sends back revisions to ensure correct references to Dr. Yancey's work are included.↗
▶Ep 56 · 14:30
clinicalWhen reviewing articles for journals, Dr. Newman now sends back revisions to ensure correct references to Dr. Yancey's work are included.↗
▶Ep 56 · 14:51
quoteWhen I review a article for a journal, I send back revisions, including, you know, making sure to use the correct references.↗
▶Ep 56 · 14:51
quoteWhen I review a article for a journal, I send back revisions, including, you know, making sure to use the correct references.↗
quoteI think one of the other things when you speak to the family, it's really important to reassure them that even if the mass increases in size and you take it out, it is likely to be a very, very low risk tumor.↗
▶Ep 3 · 11:07
epidemiologicalNocktern study showed approximately 98% event-free survival and 100% overall survival in observed prenatal neuroblastoma↗
▶Ep 3 · 11:37
guidelineAfter one year, surveillance becomes every six months, then yearly↗
▶Ep 3 · 11:37
guidelineFirst-year surveillance protocol: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spaced out to one year↗
▶Ep 3 · 13:38
quoteI will say the last one of these that I had at the 12-month scan it got bigger. And we took it out and it was a ended up being a sequestration.↗
▶Ep 3 · 16:07
guidelineLaparoscopic approach is reasonable for masses less than 6 centimeters↗
▶Ep 3 · 17:00
clinicalBiology of neuroblastoma is more important than lymph node status for treatment decisions↗
▶Ep 3 · 17:30
quoteThe biology of these tumors tend to still be good. These aren't bad neuroblastomas.↗
▶Ep 3 · 17:30
clinicalStage MS (formerly 4S) with skin lesions and liver mets still tends to have good biology↗
▶Ep 3 · 17:58
guidelineOnce respiratory compromise begins, treatment options include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 3 · 17:58
guidelineStage MS without distress can be treated with aggressive observation↗
▶Ep 3 · 17:58
quoteIf they're not in any distress, they're treated with my favorite protocol, which is aggressive observation.↗
▶Ep 3 · 19:52
clinicalLiver biopsy in newborns is difficult because bleeding is hard to control↗
▶Ep 3 · 21:05
guidelineInitial workup for abdominal mass includes ultrasound to determine solid vs cystic, then CT with PO and IV contrast if solid↗
▶Ep 3 · 21:05
clinicalVIP secretion can cause severe diarrhea in neuroblastoma↗
▶Ep 3 · 26:03
guidelinePET scan is not part of routine initial diagnostic workup but may be used for MIBG-negative soft tissue areas to distinguish recurrence from scar↗
Neuroblastoma
▶Ep 6 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 6 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 6 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 6 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 6 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 6 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 6 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 6 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 6 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 6 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 6 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 6 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 6 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 6 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 6 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 6 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 6 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 6 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 6 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 6 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 6 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 6 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 6 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 6 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 6 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 6 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 6 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
▶Ep 6 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 5 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 5 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 5 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 5 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 5 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 5 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 5 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 5 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 5 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 5 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 5 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 5 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 5 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 5 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 5 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 5 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 5 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 5 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 5 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 5 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 5 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 5 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 5 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 5 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 5 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 5 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
▶Ep 5 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 9 · 2:32
quoteI mostly am quite reassuring at this stage. It's still a bit early.↗
▶Ep 9 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 9 · 2:47
quoteI think it's important to reassure and help the mom understand that the priority during the pregnancy is the mom. And once the baby is born, then we'll learn more.↗
▶Ep 9 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 9 · 9:58
guidelineSurveillance protocol for observed neonatal masses: ultrasound and catecholamines at birth, 3 weeks, 6 weeks, 12 weeks, then spacing out through first year, then every 6 months, then yearly↗
▶Ep 9 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 9 · 13:20
guidelineCriteria for surgery in observed neonatal neuroblastoma: >50% volume increase or >50% increase in VMA or HVA↗
▶Ep 9 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 9 · 14:50
clinicalStage MS (formerly 4S) neuroblastoma with liver and skin metastases in neonates has good biology and can be observed unless respiratory compromise develops from hepatomegaly↗
▶Ep 9 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 9 · 15:42
clinicalTreatment options for MS neuroblastoma with respiratory compromise include chemotherapy, radiation, or emergent decompressive laparotomy↗
▶Ep 9 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 9 · 26:56
epidemiologicalApproximately 50% of children's hospitals now use percutaneous biopsy for suspected neuroblastoma↗
▶Ep 9 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 9 · 28:04
clinicalPercutaneous biopsy is equivalent to open biopsy for diagnosis and NMEC determination but may fail for 11q loss of heterozygosity assessment↗
▶Ep 9 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 9 · 28:55
clinicalOptimized percutaneous biopsy technique requires 10-12 cores, higher gauge needle, and pathologist present for frozen section to confirm viable tumor↗
▶Ep 9 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 9 · 29:45
clinicalOpen biopsy patients have higher risk of blood transfusion, higher narcotic use, and more frequent hospital admission compared to percutaneous biopsy↗
▶Ep 9 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 9 · 33:49
clinicalLoss of heterozygosity at 11q is the most common segmental chromosomal alteration in neuroblastoma and can elevate risk category↗
▶Ep 9 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 9 · 37:20
clinicalHigh-risk neuroblastoma patients require double-lumen external catheter (not port) for bone marrow transplant↗
▶Ep 9 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 9 · 42:40
clinicalAfter 5-6 cycles of chemotherapy, neuroblastomas become more fibrotic and harder to resect↗
▶Ep 9 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
▶Ep 9 · 52:19
quoteOne thing we try to teach the residents is that with neuroblastoma surgery, there's no reason to cause disability.↗
