David Skarda

31 timestamped statements across 1 collection — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Pancreatic Tumors · episode host

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▶ Ep 2 · 1:15
I will freely admit that my knowledge base in this subject is not incredibly deep. So basically the information that I have presented is kind of the depth of my knowledge. Once we get past that point, um, I'll be guessing probably
quote · Pancreatic Tumors
▶ Ep 2 · 20:41
It's a very bizarre benign tumor, right? Because there is a relatively, I don't know if it is 15, 20% present with metastatic disease, but it's called a benign tumor
quote · Pancreatic Tumors

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Pancreatic Tumors 31 entries

Pancreatic Tumors. Presented by David Skarda, MD 04.10.23 Video

▶ Ep 2 · 1:15
quote I will freely admit that my knowledge base in this subject is not incredibly deep. So basically the information that I have presented is kind of the depth of my knowledge. Once we get past that point, um, I'll be guessing probably ↗
▶ Ep 2 · 2:44
clinical Serous cystadenomas are benign lesions that may grow and become symptomatic, with rare case reports of malignant transformation, and about one-third are identified incidentally ↗
▶ Ep 2 · 3:27
quote these are cured by removal ↗
▶ Ep 2 · 3:27
clinical Serous cystadenomas are cured by removal ↗
▶ Ep 2 · 3:54
epidemiological Mucinous cystadenomas are more common in females and the majority are located in the tail of the pancreas ↗
▶ Ep 2 · 4:17
clinical Mucinous cystadenomas are generally considered benign but potentially pre-malignant lesions ↗
▶ Ep 2 · 4:51
clinical Mature cystic teratomas can arise anywhere within the pancreatic parenchyma and are often adjacent to the pancreas in the retroperitoneum ↗
▶ Ep 2 · 5:21
clinical Mature cystic teratomas can contain malignancy and are resected based on symptoms and malignant potential ↗
▶ Ep 2 · 17:51
quote She's cured. She is cured ↗
▶ Ep 2 · 18:21
epidemiological Solid pseudopapillary tumors occur in young women more than young men, with mean age of diagnosis 28 years ↗
▶ Ep 2 · 18:32
guideline Complete surgical resection with clear margins is the treatment of choice for solid pseudopapillary tumors, and enucleation is not considered adequate treatment ↗
▶ Ep 2 · 19:08
clinical Overall survival for solid pseudopapillary tumors is really good with complete resection, and lymph node metastases are fairly rare ↗
▶ Ep 2 · 20:41
quote It's a very bizarre benign tumor, right? Because there is a relatively, I don't know if it is 15, 20% present with metastatic disease, but it's called a benign tumor ↗
▶ Ep 2 · 20:44
clinical Solid pseudopapillary tumors can present with metastatic disease in 15-20% of cases, but survival is still quite good without adjuvant therapy after resecting the primary tumor ↗
▶ Ep 2 · 21:15
quote the cases I've seen reported, you don't have to. You just resect the primary tumor and let those metastatic deposits hang out ↗
▶ Ep 2 · 25:55
epidemiological Solid pseudopapillary tumors are the most common malignant pancreatic tumor in young children, with mean age of 5 years and twice as common in males ↗
▶ Ep 2 · 26:10
clinical Pancreatoblastoma is associated with Beckwith-Wiedemann syndrome and FAP, with some tumors having genetic abnormalities on chromosome 11p15 ↗
▶ Ep 2 · 26:58
clinical In pancreatoblastoma, alpha-fetoprotein is elevated in a fairly high percentage of cases and can be used to monitor for recurrence after resection ↗
▶ Ep 2 · 31:20
clinical Mucinous cystadenocarcinomas can be challenging to differentiate from mucinous cystadenomas and frequently have foci of dysplastic or frankly malignant epithelium, making sampling problematic ↗
▶ Ep 2 · 32:48
clinical Acinar cell adenocarcinomas in young children (around 3 years old) tend to be well-circumscribed masses, occur more commonly in males, and can be equally distributed throughout the pancreas ↗
▶ Ep 2 · 33:22
clinical Acinar cell adenocarcinomas have much better prognosis than typical ductal adenocarcinoma, and adjuvant chemotherapy or radiation is not necessary after complete resection ↗
▶ Ep 2 · 34:02
clinical Pancreatic ductal adenocarcinomas in young people are often associated with FAP, Peutz-Jeghers syndrome, or hereditary pancreatic cancer syndrome ↗
▶ Ep 2 · 36:12
clinical Insulinomas are the most common pancreatic neuroendocrine tumor and are beta islet cell neoplasms that produce excessive insulin leading to hypoglycemia ↗
▶ Ep 2 · 36:33
clinical Insulinomas tend to be small, relatively well encapsulated, and diagnosed fairly early because they produce insulin ↗
▶ Ep 2 · 36:43
guideline Whipple's triad for insulinoma diagnosis includes signs and symptoms of hypoglycemia, documented hypoglycemia during the symptomatic period, and resolution of symptoms with glucose administration ↗
▶ Ep 2 · 38:57
clinical C-peptide levels are checked to ensure hypoglycemia is not from exogenous insulin administration ↗
▶ Ep 2 · 40:46
clinical Insulinomas tend to be relatively well encapsulated and surprisingly do not have blood vessels attached to them despite being endocrine tumors ↗
▶ Ep 2 · 41:52
clinical Endoscopic ultrasound is really good at finding insulinomas and helps identify the relationship of the mass to the pancreatic duct ↗
▶ Ep 2 · 45:24
clinical Sporadic insulinomas in children are often isolated and benign, while those with MEN1 tend to be multifocal and have higher incidence of malignancy ↗
▶ Ep 2 · 46:38
epidemiological 80% of gastrinomas occur sporadically, but 20% occur in the setting of MEN1, with MEN1-associated lesions tending to be multicentric, malignant, and presenting at higher rates of metastasis ↗
▶ Ep 2 · 47:12
clinical About 60% of gastrinomas are not in the pancreas but in the wall of the duodenum, typically between the common bile duct insertion and the junction of the 2nd and 3rd portion of duodenum ↗