Danielle Walsh

98 timestamped statements across 1 collection — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Soft Tissue Sarcoma (lymph nodes) · guest expert

Featured diaries

Ep 2 · 27:50
I would not operate on this. I, I would do a CBC and a chest X-ray, and the main reason for doing those is because they're virtually always normal and it helps to reassure the family.
Ep 2 · 27:50
I would not operate on this. I, I would do a CBC and a chest X-ray, and the main reason for doing those is because they're virtually always normal and it helps to reassure the family.

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Lumps & Bumps: Soft Tissue Masses and Lesions

Ep 2 · 4:14
clinical Retinoid medications for acne are significantly associated with development of pyogenic granulomas; removal of medication often resolves the lesion
Ep 2 · 4:14
clinical Retinoid medications for acne are significantly associated with development of pyogenic granulomas; removal of medication often resolves the lesion
Ep 2 · 4:47
clinical Pyogenic granuloma surgical resection has approximately 3% recurrence rate with gross negative margins
Ep 2 · 4:47
clinical Pyogenic granuloma surgical resection has approximately 3% recurrence rate with gross negative margins
Ep 2 · 4:54
quote You do not need to take, um, a wider margin, so about a 3% recurrence rate with that.
Ep 2 · 4:54
quote You do not need to take, um, a wider margin, so about a 3% recurrence rate with that.
Ep 2 · 5:04
clinical Shave excision with curettage of pyogenic granuloma has 9.5% recurrence rate
Ep 2 · 5:04
clinical Shave excision with curettage of pyogenic granuloma has 9.5% recurrence rate
Ep 2 · 5:20
quote Silver nitrate actually has the lowest success rate, 15% recurrence rate with it.
Ep 2 · 5:20
clinical Silver nitrate treatment for pyogenic granuloma has 15% recurrence rate, the highest among treatment options
Ep 2 · 5:20
clinical Silver nitrate treatment for pyogenic granuloma has 15% recurrence rate, the highest among treatment options
Ep 2 · 5:20
quote Silver nitrate actually has the lowest success rate, 15% recurrence rate with it.
Ep 2 · 5:33
quote You're not gonna get a path specimen, and it may require multiple treatments.
Ep 2 · 5:33
quote You're not gonna get a path specimen, and it may require multiple treatments.
Ep 2 · 8:28
epidemiological In a large study, 80% of characteristic Spitz nevi involuted spontaneously
Ep 2 · 8:28
epidemiological In a large study, 80% of characteristic Spitz nevi involuted spontaneously
Ep 2 · 8:44
clinical Half of pediatric dermatologists would observe classic Spitz nevi without excision, waiting for spontaneous resolution
Ep 2 · 8:44
clinical Half of pediatric dermatologists would observe classic Spitz nevi without excision, waiting for spontaneous resolution
Ep 2 · 9:43
clinical In a series of 30 patients with incompletely removed Spitz nevi, 24 were observed and none recurred; 6 were re-excised and only 1 had residual disease
Ep 2 · 9:43
clinical In a series of 30 patients with incompletely removed Spitz nevi, 24 were observed and none recurred; 6 were re-excised and only 1 had residual disease
Ep 2 · 10:23
clinical In a retrospective study with 1-3mm margins for Spitz nevi, 20% had positive margins on re-excision
Ep 2 · 10:23
clinical In a retrospective study with 1-3mm margins for Spitz nevi, 20% had positive margins on re-excision
Ep 2 · 10:45
guideline Barnhill recommends 3-5mm margins for classic Spitz nevi, 1cm for atypical, and melanoma-protocol margins for severely atypical based on depth
Ep 2 · 10:45
guideline Barnhill recommends 3-5mm margins for classic Spitz nevi, 1cm for atypical, and melanoma-protocol margins for severely atypical based on depth
Ep 2 · 11:56
epidemiological About one-third of Spitz nevi cases had nodal micrometastases on sentinel lymph node biopsy in combined adult and pediatric series
Ep 2 · 11:56
epidemiological About one-third of Spitz nevi cases had nodal micrometastases on sentinel lymph node biopsy in combined adult and pediatric series
Ep 2 · 12:18
clinical In 8 series, 39% of Spitz nevi with sentinel lymph node biopsy were positive, but all patients remained disease-free at 3-year follow-up without further intervention
Ep 2 · 12:18
clinical In 8 series, 39% of Spitz nevi with sentinel lymph node biopsy were positive, but all patients remained disease-free at 3-year follow-up without further intervention
Ep 2 · 14:12
quote 24 patients. Uh, well, small studies. We got not a lot of these in kids, all right, but we see them. We see it. We've, I, I suspect all of us have seen at least a few.
Ep 2 · 14:12
quote 24 patients. Uh, well, small studies. We got not a lot of these in kids, all right, but we see them. We see it. We've, I, I suspect all of us have seen at least a few.
Ep 2 · 18:28
epidemiological Pediatric melanoma ABCDE criteria capture only 40% of cases in children under 10 and 60% in children over 11
Ep 2 · 18:28
epidemiological Pediatric melanoma ABCDE criteria capture only 40% of cases in children under 10 and 60% in children over 11
Ep 2 · 19:35
guideline Melanoma margin recommendations: 5mm for in situ, 1cm for ≤1mm thick, 1-2cm for 1-2mm thick, 2cm for >2mm thick
Ep 2 · 19:35
guideline Melanoma margin recommendations: 5mm for in situ, 1cm for ≤1mm thick, 1-2cm for 1-2mm thick, 2cm for >2mm thick
Ep 2 · 19:50
clinical Cochrane review suggests 2cm margins are adequate for thick melanomas; no benefit demonstrated for 4cm margins
Ep 2 · 19:50
clinical Cochrane review suggests 2cm margins are adequate for thick melanomas; no benefit demonstrated for 4cm margins
Ep 2 · 20:12
epidemiological Giant congenital nevi (>20cm) have 8% melanoma risk, higher if hairy; 60% of melanomas occur in first decade, reported as young as 3 years
Ep 2 · 20:12
epidemiological Giant congenital nevi (>20cm) have 8% melanoma risk, higher if hairy; 60% of melanomas occur in first decade, reported as young as 3 years
Ep 2 · 20:35
epidemiological Pediatric melanoma has higher metastatic rate to lymph nodes (about 25%) than adults, especially in children younger than 10 and with thicker lesions
Ep 2 · 20:35
epidemiological Pediatric melanoma has higher metastatic rate to lymph nodes (about 25%) than adults, especially in children younger than 10 and with thicker lesions
Ep 2 · 21:02
clinical If sentinel node is negative in melanoma, probability of subsequent recurrence is only about 5%
Ep 2 · 21:02
clinical If sentinel node is negative in melanoma, probability of subsequent recurrence is only about 5%
Ep 2 · 21:08
clinical If sentinel node is negative in melanoma, probability of non-sentinel node being positive is low but not zero
Ep 2 · 21:08
clinical If sentinel node is negative in melanoma, probability of non-sentinel node being positive is low but not zero
Ep 2 · 27:50
quote I would not operate on this. I, I would do a CBC and a chest X-ray, and the main reason for doing those is because they're virtually always normal and it helps to reassure the family.
Ep 2 · 27:50
quote I would not operate on this. I, I would do a CBC and a chest X-ray, and the main reason for doing those is because they're virtually always normal and it helps to reassure the family.
Ep 2 · 28:02
quote I think a 6 year old with a single node in the neck that's not growing, I think the chance of lymphoma is almost zero.
Ep 2 · 28:02
quote I think a 6 year old with a single node in the neck that's not growing, I think the chance of lymphoma is almost zero.
Ep 2 · 30:57
clinical Acute unilateral cervical lymphadenopathy is mostly bacterial (strep and staph); acute bilateral is usually viral
Ep 2 · 30:57
clinical Acute unilateral cervical lymphadenopathy is mostly bacterial (strep and staph); acute bilateral is usually viral
Ep 2 · 31:30
clinical Chronic/subacute unilateral lymphadenopathy suggests atypical mycobacteria, Bartonella, tuberculosis, or toxoplasmosis
Ep 2 · 31:30
clinical Chronic/subacute unilateral lymphadenopathy suggests atypical mycobacteria, Bartonella, tuberculosis, or toxoplasmosis
Ep 2 · 31:45
clinical Chronic/subacute bilateral lymphadenopathy suggests EBV, CMV, or HIV
Ep 2 · 31:45
clinical Chronic/subacute bilateral lymphadenopathy suggests EBV, CMV, or HIV
Ep 2 · 32:43
clinical Lymphadenopathy may persist 6-8 weeks after antibiotic treatment
Ep 2 · 32:43
clinical Lymphadenopathy may persist 6-8 weeks after antibiotic treatment
Ep 2 · 34:22
clinical Biopsy indications for cervical lymphadenopathy include: >3cm, hard/fixed, supraclavicular or epitrochlear location, multiple nodal groups, systemic symptoms, hepatosplenomegaly, significantly abnormal labs, or abnormal imaging
Ep 2 · 34:22
clinical Biopsy indications for cervical lymphadenopathy include: >3cm, hard/fixed, supraclavicular or epitrochlear location, multiple nodal groups, systemic symptoms, hepatosplenomegaly, significantly abnormal labs, or abnormal imaging
Ep 2 · 34:58
clinical FNA for lymph nodes has 90% sensitivity and specificity but 10% false rate, with higher false-negative rate in Hodgkin lymphoma
Ep 2 · 34:58
clinical FNA for lymph nodes has 90% sensitivity and specificity but 10% false rate, with higher false-negative rate in Hodgkin lymphoma
Ep 2 · 35:39
epidemiological Malignancy rate in cervical lymph node biopsies varies 10-25% overall but ranges 12-80% depending on referral patterns and specialty
Ep 2 · 35:39
epidemiological Malignancy rate in cervical lymph node biopsies varies 10-25% overall but ranges 12-80% depending on referral patterns and specialty
Ep 2 · 38:00
clinical Atypical mycobacterial lymphadenitis is a local problem in immunocompetent children, usually age 1-5 years, enters through oropharynx, and is not considered contagious
Ep 2 · 38:00
clinical Atypical mycobacterial lymphadenitis is a local problem in immunocompetent children, usually age 1-5 years, enters through oropharynx, and is not considered contagious
Ep 2 · 38:31
clinical In a randomized multicenter trial for atypical mycobacterial lymphadenitis, surgery had 96% cure rate versus 66% cure rate with antibiotics alone
Ep 2 · 38:31
clinical In a randomized multicenter trial for atypical mycobacterial lymphadenitis, surgery had 96% cure rate versus 66% cure rate with antibiotics alone
Ep 2 · 38:56
clinical In a series of 55 patients with confirmed atypical mycobacteria, 45 started on antibiotics and 30 (67%) resolved without surgery
Ep 2 · 38:56
clinical In a series of 55 patients with confirmed atypical mycobacteria, 45 started on antibiotics and 30 (67%) resolved without surgery
Ep 2 · 50:31
clinical Neonatal breast mastitis occurs mostly in term or near-term infants due to estrogen exposure; very uncommon in preemies because estrogen levels don't rise
Ep 2 · 50:31
clinical Neonatal breast mastitis occurs mostly in term or near-term infants due to estrogen exposure; very uncommon in preemies because estrogen levels don't rise
Ep 2 · 50:44
epidemiological Peak age for neonatal mastitis is 2-4 weeks; majority are staph but gram negatives reported
Ep 2 · 50:44
epidemiological Peak age for neonatal mastitis is 2-4 weeks; majority are staph but gram negatives reported
Ep 2 · 51:26
clinical Parenteral antibiotics for 7-14 days may be needed for neonatal mastitis because infants have delayed absorption and delayed antibiotic efficacy
Ep 2 · 51:26
clinical Parenteral antibiotics for 7-14 days may be needed for neonatal mastitis because infants have delayed absorption and delayed antibiotic efficacy
Ep 2 · 52:39
clinical In two small series of neonatal mastitis with I&D, breast deformity occurred in 2 of 5 patients (40%) in one study and 2 of 7 patients (29%) in another
Ep 2 · 52:39
clinical In two small series of neonatal mastitis with I&D, breast deformity occurred in 2 of 5 patients (40%) in one study and 2 of 7 patients (29%) in another
Ep 2 · 1:03:11
clinical Fibroadenomas are the most common breast lesion in the under-20 age group, representing an exaggerated response to estrogen
Ep 2 · 1:03:11
clinical Fibroadenomas are the most common breast lesion in the under-20 age group, representing an exaggerated response to estrogen
Ep 2 · 1:03:20
epidemiological About 10-15% of fibroadenomas are multiple and 10% are bilateral
Ep 2 · 1:03:20
epidemiological About 10-15% of fibroadenomas are multiple and 10% are bilateral
Ep 2 · 1:03:27
clinical Fibroadenomas typically increase in size over 6-12 months, then stabilize and can regress completely
Ep 2 · 1:03:27
clinical Fibroadenomas typically increase in size over 6-12 months, then stabilize and can regress completely
Ep 2 · 1:04:17
clinical Excisional biopsy for fibroadenoma is recommended if continuing to grow, changing, over 5cm, symptomatic, complex on ultrasound, unreliable follow-up, or severe family anxiety
Ep 2 · 1:04:17
clinical Excisional biopsy for fibroadenoma is recommended if continuing to grow, changing, over 5cm, symptomatic, complex on ultrasound, unreliable follow-up, or severe family anxiety
Ep 2 · 1:05:00
clinical Juvenile fibroadenomas are larger lesions with rapid growth, greater than 5cm, but only 10% reach that size
Ep 2 · 1:05:00
clinical Juvenile fibroadenomas are larger lesions with rapid growth, greater than 5cm, but only 10% reach that size
Ep 2 · 1:05:14
clinical Juvenile fibroadenomas larger than 5cm are difficult to distinguish from cystosarcoma phyllodes, even on percutaneous biopsy
Ep 2 · 1:05:14
clinical Juvenile fibroadenomas larger than 5cm are difficult to distinguish from cystosarcoma phyllodes, even on percutaneous biopsy
Ep 2 · 1:05:57
clinical Simple fibroadenomas (isolated, well-demarcated, solid) have no increased cancer risk if no family history and no adjacent breast tissue abnormality
Ep 2 · 1:05:57
clinical Simple fibroadenomas (isolated, well-demarcated, solid) have no increased cancer risk if no family history and no adjacent breast tissue abnormality
Ep 2 · 1:06:14
clinical Complex fibroadenomas (with cysts, calcifications, or abnormal surrounding tissue) carry a slight increased risk of future breast cancer up to 20 years after diagnosis
Ep 2 · 1:06:14
clinical Complex fibroadenomas (with cysts, calcifications, or abnormal surrounding tissue) carry a slight increased risk of future breast cancer up to 20 years after diagnosis
Ep 2 · 1:06:42
epidemiological Malignant breast disease in pediatric patients is rare and more commonly metastatic from other sites than primary breast tumors
Ep 2 · 1:06:42
epidemiological Malignant breast disease in pediatric patients is rare and more commonly metastatic from other sites than primary breast tumors
Ep 2 · 1:06:53
epidemiological Lymphoma patients treated with chest radiation at young ages have up to 25% higher incidence of malignant breast disease
Ep 2 · 1:06:53
epidemiological Lymphoma patients treated with chest radiation at young ages have up to 25% higher incidence of malignant breast disease
Ep 2 · 1:07:05
guideline American Society of Clinical Oncology discourages BRCA genetic testing before age 20 due to lack of timely medical benefit and psychosocial risks
Ep 2 · 1:07:05
guideline American Society of Clinical Oncology discourages BRCA genetic testing before age 20 due to lack of timely medical benefit and psychosocial risks