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Pharmacologic Therapies

items total cited expert statements Updated Nov 6, 2026
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Clinical Outcomes2 items
Clinical outcomes of teduglutide therapy in children with short bowel syndrome-associated intestinal failure: A single-center experience
Background: Short bowel syndrome-associated intestinal failure (SBS-IF) requires long-term parenteral nutrition (PN), increasing the risk of complications such as central line associated bloodstream infections, sepsis and liver disease. Ted
article · Nov 2026
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Teduglutide's Impact on Short Bowel Syndrome: Reducing TPN Needs and Promoting Rehabilitation w/ Dr. Paul Wales
Dr. Paul Wales discusses the therapeutic benefits of teduglutide for patients with Short Bowel Syndrome (SBS). He explains how this altered hormone analog addresses the short half-life of the native hormone, leading to a significant 40% red
video0:32 · Oct 2026
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Cost-Utility Analysis1 item
Cost-utility analysis of teduglutide compared to standard care in weaning parenteral nutrition support in children with short bowel syndrome
Background & Aims: A growing proportion of children with short bowel syndrome (SBS) remain dependent on long-term parenteral nutrition (PN). Teduglutide offers the potential for more children to decrease PN support and achieve enteral auton
article · Nov 2026
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Association between 4%-tetrasodium EDTA and sepsis in neonatal piglets: A retrospective cohort study.
Central line-associated bloodstream infections are a major concern for children with intestinal failure and in animal research using parenteral nutrition (PN). In neonatal piglets receiving PN, we compared sepsis, line occlusions, line repl
article · Nov 2026
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Cost-utility analysis of 4% tetrasodium ethylenediaminetetraacetic acid, taurolidine, and heparin lock to prevent central line-associated bloodstream infections in children with intestinal failure.
Central line-associated bloodstream infections (CLABSI) are a serious complication in children with intestinal failure. This study assessed the incremental costs of 4% tetrasodium ethylenediaminetetraacetic acid (EDTA) compared with tauroli
article · Nov 2026
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