Paul Wales · Association between 4%-tetrasodium EDTA and sepsis in neonatal piglets: A retrospective cohort study.
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Article1 min read·Published Nov 2026

Association between 4%-tetrasodium EDTA and sepsis in neonatal piglets: A retrospective cohort study.

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Article · Nov 2026 · 1 min read

In brief

In brief

Retrospective cohort study evaluating 4%-tetrasodium EDTA catheter lock solution in neonatal piglets receiving parenteral nutrition. Compares infection rates, line complications, mortality, and cost-effectiveness between EDTA-treated and control groups in an animal model relevant to pediatric intestinal failure.

Written by the GCMD Library team from the article.

Paul Wales

Central line-associated bloodstream infections are a major concern for children with intestinal failure and in animal research using parenteral nutrition (PN). In neonatal piglets receiving PN, we compared sepsis, line occlusions, line replacements, mortality, and costs with and without the use of a 4%-tetrasodium ethylenediaminetetraacetic acid (T-EDTA) locking solution. We performed a retrospect…

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