SCCOHT and HIPEC: Before or After Chemotherapy?
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Carousel1 min read·Published Oct 2026

SCCOHT and HIPEC: Before or After Chemotherapy?

Slide presenting a pediatric oncology case: 1-year-old with anemia and abdominal mass diagnosed with SCCOHT ovarian tumor.
Slide explaining SCCOHT's brief chemosensitivity window and need for immediate intensive systemic therapy.
Flow diagram showing HIPEC treatment sequence after systemic chemotherapy in pediatric oncology.
Blue slide emphasizing immediate chemotherapy for SCCOHT while discussing HIPEC and stem cell rescue limitations.
Final slide inviting viewers to follow for more pediatric surgery education content on oncology.
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Carousel · Oct 2026 · 1 min read

In brief

In brief

Educational carousel addressing the optimal timing of hyperthermic intraperitoneal chemotherapy (HIPEC) in relation to systemic chemotherapy for small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Explores treatment sequencing considerations in this rare pediatric malignancy.

Written by the GCMD Library team from the carousel.

Slides

6 pages · click to turn to one
Pediatric surgical oncology. A social-media carousel made possible by Cincinnati Children's.
The text on each slide
  1. Oncology | Expert-to-Expert | Made possible by Cincinnati Children's | A 1-year-old with anemia on routine labs and a right-sided abdominal mass. Diagnosis: SCCOHT, the most aggressive ovarian tumor. HIPEC is part of the plan. | DOES IT GO BEFORE CHEMOTHERAPY, OR AFTER? | 1/6
  2. Oncology | Clinical Foundations | Made possible by Cincinnati Children's | THE ANSWER: CHEMOTHERAPY FIRST | THE WINDOW OF CHEMOSENSITIVITY IS SHORT | SCCOHT responds to chemotherapy, but only transiently. | Intensive systemic therapy starts right away, ahead of any further staging or second-look surgery. | 2/6
  3. Oncology | Clinical Foundations | Made possible by Cincinnati Children's | THE SEQUENCE | HIPEC COMES AFTER THE CHEMOTHERAPY | SYSTEMIC CHEMO → CYTO-REDUCTION → HIPEC (CISPLATIN) → STEM CELL RESCUE | Surgery removes what chemotherapy leaves, heated cisplatin treats the peritoneal surfaces, and autologous stem cell rescue follows. | 3/6
  4. Oncology | Clinical Foundations | Made possible by Cincinnati Children's | WHAT CHANGES IN A CHILD THIS SMALL | Roshni Dasgupta, MD, MPH | Professor, Director Surgical Oncology, Cincinnati Children's | 4/6
  5. Oncology | Clinical Foundations | Made possible by Cincinnati Children's | THE TAKEAWAY | CHEMOTHERAPY FIRST, WHILE THE WINDOW IS OPEN | HIPEC and stem cell rescue remain an institutional approach in SCCOHT, with limited evidence and wide variation between centers. | Whatever comes next, systemic therapy starts now. | 5/6
  6. Oncology | Clinical Foundations | Made possible by Cincinnati Children's | FOLLOW FOR MORE PEDIATRIC SURGERY EDUCATION. | 6/6
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