Venous thromboembolism following inpatient pediatric surgery: Analysis of 153,220 patients
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Read the article on jpedsurg.org ↗Article · Oct 2018 · 1 min read
In brief
In brief
Large-scale analysis of over 153,000 pediatric surgical patients reveals 0.20% VTE incidence, with highest rates in cardiothoracic surgery (0.72%). Most events occur within 9 days and before discharge, with VTE patients showing 6-fold higher mortality, emphasizing need for risk stratification and prophylaxis protocols.
Written by the GCMD Library team from the article.
Purpose
To evaluate venous thromboembolism (VTE) rates and risk factors following inpatient pediatric surgery.
Methods
153,220 inpatient pediatric surgical patients were selected from the 2012–2015 NSQIP-P database. Demographic and perioperative variables were documented. Primary outcome was VTE requiring treatment within 30 postoperative days. Secondary outcomes included length of stay (LOS) and 30-day mortality. Prediction models were generated using logistic regression. Mortality and time to VTE were assessed using Kaplan–Meier survival analysis.
Results
305 patients (0.20%) developed 296 venous thromboses and 12 pulmonary emboli (3 cooccurrences). Median time to VTE was 9 days. Most VTEs (81%) occurred predischarge. Subspecialties with highest VTE rates were cardiothoracic (0.72%) and general surgery (0.28%). No differences were seen for elective vs. urgent/emergent procedures (p = 0.106). All-cause mortality VTE patients was 1.2% vs. 0.2% in patients without VTE (p