Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site.
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Nov 2026 · 1 min read
In brief
In brief
This study presents an improved transplantation technique for human intestinal organoids using the mouse mesentery as an engraftment site, offering a more physiologically relevant alternative to kidney capsule transplantation. The mesenteric approach better mimics native intestinal anatomy and may enhance organoid maturation for disease modeling and regenerative medicine applications.
Written by the GCMD Library team from the article.
Statements in this article
Human intestinal organoids have been previously transplanted into the mouse kidney capsule for in vivo maturation studies.
Transplantation into the mouse mesentery provides a more physiologic and anatomic engraftment site compared to the kidney capsule.