Tranexamic Acid in Pediatric Combat Trauma Requiring Massive Transfusions and Mortality
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Read the article on bit.ly ↗Article · Jun 2020 · 1 min read
In brief
In brief
Study examining tranexamic acid effectiveness in pediatric combat trauma patients requiring massive transfusions, using Department of Defense Trauma Registry data. Addresses critical knowledge gap in pediatric hemorrhage control, as existing TXA evidence is primarily from adult populations and limited pediatric combat settings.
Written by the GCMD Library team from the article.
Background: Tranexamic acid (TXA) has been demonstrated to decrease mortality in adult trauma, particularly in those with massive transfusions needs sustained in combat injury. Limited data is available for the efficacy of TXA in pediatric trauma patients outside of a single Combat Support Hospital in Afghanistan.
Methods: The Department of Defense Trauma Registry (DODTR) was queried for trauma patients