Tissue engineering: from the bedside to the bench and back to the bedside
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In brief
In brief
This review traces the 30-year evolution of tissue engineering and regenerative medicine from laboratory science to clinical application, highlighting the pioneering role of pediatric surgeons in advancing the field. While the technology has not yet reached its full potential, several therapies have successfully progressed from concept to patient care, particularly in pediatric surgical populations.
Written by the GCMD Library team from the article.
Abstract
The field of Tissue Engineering and Regenerative Medicine has evolved rapidly over the past thirty years. This review will summarize its history, current status and direction through the lens of clinical need, its progress through science in the laboratory and application back into patients. We can take pride in the fact that much effort and progress began with the surgical problems of children and that many surgeons in the pediatric surgical specialties have become pioneers and investigators in this new field of science, engineering, and medicine. Although the field has yet to fulfill its great promise, there have been several examples where a therapy has progressed from the first idea to human application within a short span of time and, in many cases, it has been applied in the surgical care of children.